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LY-3177833

LY-3177833 Structure
LY-3177833 structure
CAS No.
1627696-51-8
Chemical Name:
LY-3177833
Synonyms
CS-2783;LY-3177833;LY 3177833;LY-3177833;LY3177833,CDK,Cyclin dependent kinase,Inhibitor,inhibit,LY 3177833;(R)-3-(5-fluoropyrimidin-4-yl)-3-methyl-6-(1H-pyrazol-4-yl)isoindolin-1-one;1H-Isoindol-1-one, 3-(5-fluoro-4-pyrimidinyl)-2,3-dihydro-3-methyl-6-(1H-pyrazol-4-yl)-, (3R)-
CBNumber:
CB93139438
Molecular Formula:
C16H12FN5O
Molecular Weight:
309.3
MDL Number:
MFCD30533280
MOL File:
1627696-51-8.mol
Last updated:2023-06-08 09:03:09
Request For Quotation

LY-3177833 Properties

Boiling point 660.7±55.0 °C(Predicted)
Density 1.398±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO:30.0(Max Conc. mg/mL);96.99(Max Conc. mM)
form A crystalline solid
pka 11.67±0.40(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
GHS05,GHS07,GHS08
Signal word  Danger
Hazard statements  H302-H315-H318-H334-H317-H341-H361-H370-H335-H413
Precautionary statements  P201-P202-P260-P264-P270-P272-P273-P280-P284-P301+P312-P302+P352-P304+P341-P305+P351+P338-P310-P308+P313-P321-P330-P362+P364-P333+P313-P342+P311-P363-P405-P501
NFPA 704
0
3 0

LY-3177833 price More Price(10)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 25988 LY3177833 ≥98% 1627696-51-8 5mg $93 2024-03-01 Buy
Cayman Chemical 25988 LY3177833 ≥98% 1627696-51-8 10mg $166 2024-03-01 Buy
Cayman Chemical 25988 LY3177833 ≥98% 1627696-51-8 25mg $388 2024-03-01 Buy
Cayman Chemical 25988 LY3177833 ≥98% 1627696-51-8 50mg $728 2024-03-01 Buy
AK Scientific 7406DY CID81689696 1627696-51-8 50mg $910 2021-12-16 Buy
Product number Packaging Price Buy
25988 5mg $93 Buy
25988 10mg $166 Buy
25988 25mg $388 Buy
25988 50mg $728 Buy
7406DY 50mg $910 Buy

LY-3177833 Chemical Properties,Uses,Production

Description

LY3177833 is an orally bioavailable inhibitor of Cdc7 kinase (IC50 = 3.3 nM for ADP production in an enzyme assay). It inhibits phosphorylation of MCM2-S53 in H1299 cells (IC50 = 0.29 μM). LY3177833 reduces tumor growth in an SW620 human colorectal adenocarcinoma mouse xenograft model when administered at doses of 10, 20, and 30 mg/kg twice per day.

LY-3177833 Preparation Products And Raw materials

Raw materials

Preparation Products

LY-3177833 Suppliers

Global( 47)Suppliers
Supplier Tel Email Country ProdList Advantage
career henan chemical co 		+86-0371-86658258 15093356674; factory@coreychem.com China 29826 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		86-571-88216897,88216896 13588875226 sales@hzclap.com CHINA 6313 58
Zhejiang J&C Biological Technology Co.,Limited 		+1-2135480471 +1-2135480471 sales@sarms4muscle.com China 10523 58
InvivoChem 		+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6393 58
TargetMol Chemicals Inc. 		+1-781-999-5354 support@targetmol.com United States 19973 58
ShenZhen Trendseen Biological Technology Co.,Ltd. 		13417589054 trendseenbio@gmail.com China 11681 58
Aladdin Scientific 		+1-833-552-7181 sales@aladdinsci.com United States 52927 58
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131980 58
Shanghai Boyle Chemical Co., Ltd. sales@boylechem.com China 2923 55
Chembest Research Laboratories Limited 021-20908456 sales@BioChemBest.com China 6010 61
Supplier Advantage
career henan chemical co 		58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		58
Zhejiang J&C Biological Technology Co.,Limited 		58
InvivoChem 		58
TargetMol Chemicals Inc. 		58
ShenZhen Trendseen Biological Technology Co.,Ltd. 		58
Aladdin Scientific 		58
Amadis Chemical Company Limited 		58
Shanghai Boyle Chemical Co., Ltd. 55
Chembest Research Laboratories Limited 61

View Lastest Price from LY-3177833 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
LY3177833 pictures 2020-01-02 LY3177833
1627696-51-8
 US $1.00 / KG 1KG Min98% HPLC g/kg/ton Career Henan Chemical Co
  • LY3177833 pictures
  • LY3177833
    1627696-51-8
  • US $1.00 / KG
  • Min98% HPLC
  • Career Henan Chemical Co

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1of4

LY-3177833 (R)-3-(5-fluoropyrimidin-4-yl)-3-methyl-6-(1H-pyrazol-4-yl)isoindolin-1-one LY 3177833;LY-3177833 CS-2783 1H-Isoindol-1-one, 3-(5-fluoro-4-pyrimidinyl)-2,3-dihydro-3-methyl-6-(1H-pyrazol-4-yl)-, (3R)- LY3177833,CDK,Cyclin dependent kinase,Inhibitor,inhibit,LY 3177833 1627696-51-8