카리소프로돌
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카리소프로돌 속성
- 녹는점
- 92-92°C
- 끓는 점
- 403.59°C (rough estimate)
- 밀도
- 1.1035 (rough estimate)
- 굴절률
- 1.4560 (estimate)
- 저장 조건
- 2-8°C
- 용해도
- 물에 아주 약간 용해되며, 아세톤, 알코올 및 염화메틸렌에 잘 용해됩니다.
- 물리적 상태
- 고체
- 물리적 상태
- 단단한 모양
- 산도 계수 (pKa)
- pKa 4.2 (Uncertain)
- 색상
- 흰색에서 황백색까지
- 수용성
- 19.5&C에서 <0.1g/100mL
- BCS Class
- 2/4
- CAS 데이터베이스
- 78-44-4(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
위험품 표기 | Xn | ||
---|---|---|---|
위험 카페고리 넘버 | 22 | ||
안전지침서 | 36 | ||
RTECS 번호 | FB3325000 | ||
HS 번호 | 29224999 | ||
유해 물질 데이터 | 78-44-4(Hazardous Substances Data) | ||
독성 | LD50 in mice, rats (mg/kg): 2340, 1320 orally; 980, 450 i.p. (Berger) | ||
기존화학 물질 | KE-23962 |
카리소프로돌 C화학적 특성, 용도, 생산
개요
Carisoprodol (Item No. 30778) is an analytical reference standard categorized as a skeletal muscle relaxant. It also has sedative properties. Carisoprodol is regulated as a Schedule IV compound in the United States. This product is intended for research and forensic applications.화학적 성질
White Solid용도
Muscle relaxant (skeletal)Carisoprodol has an onset of action of ca. 30min and a duration of 4–6h. It is administered orally. Presumably, it acts by inhibiting interneuronal activity in the spinal cord and the brainstem reticular formation. Clinically effective doses are accompanied by drowsiness or dizziness; its mechanism may involve sedation.Its CNS depressant effects are additive with those of ethanol and other psychotropic agents. Carisoprodol has a low potential for drug dependence.
정의
ChEBI: A carbamate ester that is the mono-N-isopropyl derivative of meprobamate (which is a significant metabolite). Carisoprodol interrupts neuronal communication within the reticular formation and spinal cord, resulting in sedation and alter tion in pain perception. It is used as a muscle relaxant in the symptomatic treatment of musculoskeletal conditions associated with painful muscle spasm.제조 방법
Carisoprodol is Prepared by reaction of 2-methyl-2-propyl-1,3-pro-panediol with phosgene and ammonium hydroxide, then with isopropyl isocyanate.일반 설명
Carisoprodol, N-isopropyl-2-methyl-2-propyl-1,3-propanediol dicarbamate, 2-methyl-2-propyl-1,3-propanediol carbamate isopropylcarbamate(Soma), is the mono-N-isopropyl–substituted relative ofmeprobamate. The structure is given in the discussion ofmeprobamate. It is indicated in acute skeletomuscular conditionscharacterized by pain, stiffness, and spasm. As canbe expected, a major side effect of the drug is drowsiness.공기와 물의 반응
Insoluble in water.반응 프로필
Carisoprodol is a carbamate ester. Carbamates are chemically similar to, but more reactive than amides. Like amides they form polymers such as polyurethane resins. Carbamates are incompatible with strong acids and bases, and especially incompatible with strong reducing agents such as hydrides. Flammable gaseous hydrogen is produced by the combination of active metals or nitrides with carbamates. Strongly oxidizing acids, peroxides, and hydroperoxides are incompatible with carbamates.건강위험
SYMPTOMS: The most common symptoms of exposure to Carisoprodol are drowsiness and hives. Other symptoms may include nausea, vomiting, epigastric distress, vertigo, ataxia, tremors, agitation, irritability, headache, insomnia, fainting, hiccups, visual disturbances, asthma, fever, hypotension, excitement and paralysis.화재위험
Flash point data for Carisoprodol are not available, but Carisoprodol it probably combustible.카리소프로돌 준비 용품 및 원자재
원자재
이소프로필아민
시안산염
1,3-프로판디올,2-(2,2-디에톡시에틸)-,모노아세테이트,(R)-
포스겐
2-(hydroxymethyl)-2-methylpentyl isopropyl-carbamate
5-메틸-5-프로필-1,3-디옥산-2-온
2-메틸-2-프로필-1,3-프로판디올
Trichloroacetyl isocyanate
준비 용품
카리소프로돌 공급 업체
글로벌( 324)공급 업체
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