Carprofen
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Carprofen 속성
- 녹는점
- 186-1880C
- 끓는 점
- 509.1±35.0 °C(Predicted)
- 밀도
- 1.2011 (rough estimate)
- 굴절률
- 1.5200 (estimate)
- 저장 조건
- Sealed in dry,2-8°C
- 용해도
- DMSO: 용해성20mg/mL, 투명
- 물리적 상태
- 가루
- 산도 계수 (pKa)
- 4.84±0.30(Predicted)
- 색상
- 흰색에서 베이지색
- Merck
- 14,1862
- InChI
- InChI=1S/C15H12ClNO2/c1-8(15(18)19)9-2-4-11-12-7-10(16)3-5-13(12)17-14(11)6-9/h2-8,17H,1H3,(H,18,19)
- InChIKey
- PUXBGTOOZJQSKH-UHFFFAOYSA-N
- SMILES
- N1C2=C(C=C(Cl)C=C2)C2=C1C=C(C(C)C(O)=O)C=C2
- CAS 데이터베이스
- 53716-49-7(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | T,Xn | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 25-36/37/38-20/21/22 | ||
| 안전지침서 | 45-36-26 | ||
| 유엔번호(UN No.) | UN 2811 | ||
| WGK 독일 | 3 | ||
| RTECS 번호 | FE3180000 | ||
| 위험 등급 | 6.1 | ||
| 포장분류 | III | ||
| HS 번호 | 29339900 | ||
| 독성 | LD50 orally in mice: 400 mg/kg (Berger, Corraz) |
Carprofen C화학적 특성, 용도, 생산
개요
Carprofen is a non-steroidal anti-inflammatory drug (NSAID) commonly used in animals to combat pain and inflammation, particularly as associated with osteoarthritis. Like many NSAIDs, carprofen inhibits both cyclooxygenases COX-1 and COX-2 (IC50s = 22.3 and 3.9 μM, respectively). It also inhibits fatty acid amide hydrolase (IC50 = 74 μM), blocking the metabolism of the cannabinoid receptor ligand, arachidonoyl ethanolamide .화학적 성질
Off-White Crystalline Solid용도
Carprofen is a non steroidal anti-inflammatory that is used by veterinarians for the relief of arthritic systems in dogs. It can be used for joint pain or post operative inflammation. Carprofen, is al so used for the relief from pain and inflammation associated with osteoarthritis, hip dysplasia and other joint issues.정의
ChEBI: Propanoic acid in which one of the methylene hydrogens is substituted by a 6-chloro-9H-carbazol-2-yl group. A non-steroidal anti-inflammatory drug, it is no longer used in human medicine but is still used for treatment of arthritis in elderly dogs.부작용
Common side effects of Carprofeng in dogs include vomiting, diarrhoea, loss of appetite, constipation, behavioural changes; and in severe cases, black stools, gastrointestinal ulcers and gastrointestinal haemorrhage, jaundice, skin changes, involuntary muscle movements, and kidney damage (increased thirst, increased urination, and refusal to eat).Carprofen 준비 용품 및 원자재
원자재
수산화나트륨
사염화-1,4-벤조퀴논
염산
9H-Carbazole-2-acetic acid, 6-chloro-α-methylene-
Ethanone,1,1'-(9H-carbazole-2,9-diyl)bis-
카르프로펜에틸에스테르(카르프로펜불순물)
9H-Carbazole-2-acetic acid, 6-chloro-a-Methyl-, Methyl ester
4-나이트로아닐린
준비 용품
Carprofen 공급 업체
글로벌( 418)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Xi’an Sengmei Biotech Co.,Ltd. | +8615398038360 |
lionel@accenturebio.com | China | 288 | 58 |
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 |
sales@hbmojin.com | China | 12468 | 58 |
| Hebei Duling International Trade Co. LTD | +8617333973358 |
sales01@hbduling.cn | China | 15664 | 58 |
| Zibo Shiji Zhonglian Medical Technology Co., Ltd. | 15069388126 15069388126 |
sales@sjzlpharm.com | China | 61 | 58 |
| Xiamen Wonderful Bio Technology Co., Ltd. | +8613043004613 |
Sara@xmwonderfulbio.com | China | 305 | 58 |
| Anhui Ruihan Technology Co., Ltd | +8617756083858 |
daisy@anhuiruihan.com | China | 994 | 58 |
| Nantong Guangyuan Chemicl Co,Ltd | +undefined17712220823 |
admin@guyunchem.com | China | 616 | 58 |
| Shanghai Affida new material science and technology center | +undefined15081010295 |
admin@oudaxin.com | China | 390 | 58 |
| Shaanxi TNJONE Pharmaceutical Co., Ltd | +8618740459177 |
sarah@tnjone.com | China | 1142 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29797 | 60 |