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methoxamine

methoxamine 구조식 이미지

카스 번호:: 390-28-3

상품명:: methoxamine

동의어(영문):: Methoxamin;Methoxamedrine;Methoxamine (6CI);Pseudomethoxamine;methoxamine USP/EP/BP;(2S)-Methoxamine oxalate salt;2-Amino-1-(2,5-dimethoxyphenyl)propan-1-ol;a-(1-Aminoethyl)-2,5-dimethoxybenzyl alcohol;α-(1-Aminoethyl)-2,5-dimethoxybenzyl alcohol;α-(1-Aminoethyl)-2,5-dimethoxybenzenemethanol

CBNumber:: CB0882136

분자식:: C11H17NO3

포뮬러 무게:: 211.26

MOL 파일:: 390-28-3.mol

속성

안전

용도

공급 업체 17

methoxamine 속성

녹는점: 85-86 °C

끓는 점: 368.4±42.0 °C(Predicted)

밀도: 1.117±0.06 g/cm3(Predicted)

산도 계수 (pKa): 11.87±0.45(Predicted)

안전

methoxamine C화학적 특성, 용도, 생산

Originator

Vasoxyl ,Burroughs-Wellcome,US,1949

Manufacturing Process

2,5-Dimethoxypropiophenone is treated in absolute ether with methyl nitrite and hydrogen chloride. The hydrochloride of 2,5-dimethoxy-αisonitrosopropiophenone crystallizes out of the solution. It is removed, the base is liberated and crystallized from benzene-heptane forming yellow leaflets that melt at about 97° to 98°C. This isonitrosoketone is dissolved in absolute alcohol containing an excess of hydrogen chloride and is hydrogenated with palladized charcoal, yielding β-(2,5-dimethoxyphenyl)-βketoisopropylamine hydrochloride, a salt that melts at about 176°C with decomposition.
12.3 g (1/20 mol) of β-(2,5-dimethoxyphenyl)-β-ketoisopropylamine hydrochloride (MP 176°C) is dissolved in 50 cc of water and hydrogenated with platinum oxide platinum black in the customary Adams-Burgess Parr apparatus. About 1/20 mol of hydrogen is absorbed, after which the solution is filtered off from the catalyst, evaporated to dryness in vacuo and recrystallized from absolute alcohol, absolute ether being added to decrease solubility. The hydrochloride is thus obtained in substantially theoretical yield. It crystallizes in plates and melts at 215°C.

Therapeutic Function

Hypertensive

methoxamine 준비 용품 및 원자재

원자재

2,5-DIMETHOXYPROPIOPHENONE 메틸 니트리트 수소

준비 용품

methoxamine 공급 업체

글로벌( 17)공급 업체

공급자	전화	이메일	국가	제품 수	이점
Shaanxi Dideu Medichem Co. Ltd	+86-29-87569265 +86-18612256290	1056@dideu.com	China	3131	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Career Henan Chemica Co	+86-0371-86658258 15093356674;	laboratory@coreychem.com	China	30255	58
Shaanxi Dideu Medichem Co. Ltd	+86-029-89586680 +86-18192503167	1026@dideu.com	China	9126	58
Dayang Chem (Hangzhou) Co.,Ltd.	571-88938639 +8617705817739	info@dycnchem.com	CHINA	52867	58
GIHI CHEMICALS CO.,LIMITED	+8618058761490	info@gihichemicals.com	China	50002	58
Beijing HuaMeiHuLiBiological Chemical	010-56205725	waley188@sohu.com	China	12338	58
SynAsst Chemical.	021-60343070		China	12742	55
Shaanxi DIDU pharmaceutical and Chemical Co., Ltd	17691182729 18161915376	1046@dideu.com	China	10010	58
Shanghai Beiwanta Biotechnology Co., Ltd.	021-67187366 19901745723	info@bwtlab.com	China	9247	58

methoxamine 관련 검색:

NIFE디솔 Disodium β-glycerophosphate hydrate Adenosine Homovanillic acid Phloroglucinol Trimethoprim Bumetanide 1-(2,6-Dimethylphenoxy)-2-propanamine 2,5-DIMETHOXYBENZYL ALCOHOL Butoxamin METHOXAMINE HYDROCHLORIDE Butoxamine hydrochloride isopropylmethoxamine (+/-)-BUTOXAMINE methoxamine (2,5-DIMETHOXYPHENYL)(2-PIPERIDINYL)METHANOL