에스트리올
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에스트리올 속성
- 녹는점
- 280-282 °C(lit.)
- 알파
- D25 +58° ±5° (0.04 g in 1 ml dioxane)
- 끓는 점
- 370.61°C (rough estimate)
- 밀도
- 1.27
- 굴절률
- 58 ° (C=0.4, Dioxane)
- 인화점
- 9℃
- 저장 조건
- 2-8°C
- 용해도
- 물에는 거의 녹지 않으며, 에탄올에는 거의 녹지 않습니다(96%).
- 산도 계수 (pKa)
- pKa 10.38±0.02(H2O t=23±2 Iunspeci?ed) (Uncertain)
- 색상
- 흰색에서 황백색까지
- 수용성
- 3.2mg/L(25℃)
- Merck
- 3707
- BRN
- 2508172
- InChIKey
- PROQIPRRNZUXQM-ZXXIGWHRSA-N
- CAS 데이터베이스
- 50-27-1(CAS DataBase Reference)
- NIST
- Estriol(50-27-1)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | T,F | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 60-61-40-45-39/23/24/25-23/24/25-11 | ||
| 안전지침서 | 53-22-36/37/39-45-36/37-16 | ||
| 유엔번호(UN No.) | UN1230 - class 3 - PG 2 - Methanol, solution | ||
| WGK 독일 | 3 | ||
| RTECS 번호 | KG8225000 | ||
| F 고인화성물질 | 8-10 | ||
| HS 번호 | 29072990 | ||
| 유해 물질 데이터 | 50-27-1(Hazardous Substances Data) | ||
| 독성 | LD50 oral in rat: > 2gm/kg |
에스트리올 C화학적 특성, 용도, 생산
개요
Estriol is significantly less active than estradiol; however, it has a selective ability to stimulate blood flow and restoration of genital epithelium. In addition, using this drug reduces mental symptoms of menopausal syndrome. It is used in the premenopausal and menopausal periods, for skin atrophy and signs of genital degeneration, and so on.화학적 성질
White or almost white, crystalline powder.용도
A metabolite of Estradiol. An estrogenic metabolite considerably less potent than the hormone Estradiol정의
ChEBI: A 3-hydroxy steroid that is estra-1,3,5(10)-trien-3-ol substituted by additional hydroxy groups at positions 16 and 17 (16alpha,17beta-stereoisomer).일반 설명
Estriol, estra-1,3,5(10)-triene-3,16 ,17 -triol, is available for compounding into several differentformulations for use in HRT. It can be used alone or in combinationswith estradiol (Bi-Est) or with estradiol and estrone(Tri-Est).위험도
A carcinogen (OSHA).Safety Profile
Suspected carcinogen with experimental carcinogenic, neoplastigenic, tumorigenic, and teratogenic data. Other experimental reproductive effects. Mutation data reported. A steroid drug for the treatment of menopause. When heated to decomposition it emits acrid smoke and irritating fumes.Purification Methods
Crystallise estriol from EtOH/ethyl acetate. Also purify it by countercurrent distribution with cyclohexane/EtOAc (1:1) and EtOH/H2O (1:1). The UV (EtOH) has max at 280nm ( 2,090 M-1cm-1). [Huffmann & Lott 71 719 1949, Leeds et al. J Am Chem Soc 76 2943 1954, Beilstein 6 IV 7550.]에스트리올 준비 용품 및 원자재
원자재
에스트론
2,4-Dibromo-β-D-Glucopyranosiduronic Acid Estrane Derivative
3,16alpha-dihydroxyestra-1,3,5(10)-trien-17-one 3,16-diacetate
16α,17α-Epoxy-1,3,5(10)-estratriene-3,17β-diol diacetate
1,3,5[10]-ESTRATRIENE-3,16ALPHA-DIOL-17-ONE
16-EPIESTRIOL
2,4,16a-Tribromoestrone
2,4-Dibromo-16a-hydroxyestrone
estra-1,3,5(10),16-tetraene-3,17-diol diacetate
17-BETA-ESTRADIOL 3-METHYL ETHER
준비 용품
에스트리올 공급 업체
글로벌( 594)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Hebei Bonster Technology Co.,Limited | +8613315996897 |
bsterltd.wendy@gmail.com | China | 796 | 58 |
| Hubei Lange Biotechnology Co., Ltd. | +8617762501948 |
sales2@langebiotech.com | China | 154 | 58 |
| Wuhan senwayer century chemical Co.,Ltd | +undefined-27-86652399 +undefined13627115097 |
market02@senwayer.com | China | 881 | 58 |
| Shenzhen Monkono Technology Co.,Ltd | +86-17063441314 |
sansbiotech@outlook.com | China | 677 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 |
eric@witopchemical.com | China | 23556 | 58 |
| Shanghai Aosiris new Material Technology Co., LTD | 86-15139564871 +8615139564871 |
wrjmoon2000@163.com | China | 357 | 58 |
| Shandong Hanjiang Chemical Co., Ltd | +86-0533-2066820 +8618369939125 |
hanson@sdhanjiang.com | China | 889 | 58 |
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 |
sales@hbmojin.com | China | 12470 | 58 |
| Hebei Yanxi Chemical Co., Ltd. | +8617531190177 |
peter@yan-xi.com | China | 6001 | 58 |
| Dorne Chemical Technology co. LTD | +86-13583358881 +86-18560316533 |
Ethan@dornechem.com | China | 293 | 58 |
에스트리올 관련 검색:
에스트리올
Motolimod
β-Estradiol
ESTRIOL TRISULFATE TRISODIUM SALT,ESTRIOL TRISULPHATE, TRISODIUM SALT
ESTETROL
ESTRIOL 16,17-DIACETATE
quinestradol
ESTRIOL 3-BENZYL ETHER
ESTRIOL IMPURITY A
ESTRIOL 16-GLUCURONIDE,ESTRIOL 16ALPHA-(BETA-D-GLUCURONIDE)
9,11-Didehydroestriol
ESTRIOL IMP. B (EP): 3-HYDROXYESTRA-1,3,5(10)-TRIEN-17-ONE (ESTRONE)
EPIMESTROL
Quinestrol
Nilestriol
16beta,17beta-Estriol,3,16beta,17beta-Estriol
estriol succinate
6-KETOESTRIOL