anemonin

anemonin 구조식 이미지
카스 번호:
508-44-1
상품명:
anemonin
동의어(영문):
ANEMONIN(P);Anemonin (6CI);Anemone camphor;Pulsatilla camphor;Anemonin/Pulsatilla camphor;1,7-dioxadispiro[4.0.4^{6}.2^{5}]dodeca-3,9-diene-2,8-dione;(5S,6S)-1,7-dioxadispiro[4.0.4.2]dodeca-3,9-diene-2,8-dione ;1,7-dioxadispiro[4.0.4^{6}.2^{5}]dodeca-3,9-diene-2,8-quinone;(5R,6R)-rel-1,7-Dioxadispiro[4.0.4.2]dodeca-3,9-diene-2,8-dione;1,7-Dioxadispiro[4.0.4.2]dodeca-3,9-diene-2,8-dione, (5R,6R)-rel-
CBNumber:
CB21346666
분자식:
C10H8O4
포뮬러 무게:
192.17
MOL 파일:
508-44-1.mol
MSDS 파일:
SDS

anemonin 속성

녹는점
157-158℃
끓는 점
248.14°C (rough estimate)
밀도
1.45
굴절률
1.4440 (estimate)
InChI
InChI=1/C10H8O4/c11-7-1-3-9(13-7)5-6-10(9)4-2-8(12)14-10/h1-4H,5-6H2/t9-,10-/s3
InChIKey
JLUQTCXCAFSSLD-DPIMBTEZNA-N
SMILES
O1[C@]2(CC[C@]32C=CC(=O)O3)C=CC1=O |&1:1,4,r|

안전

독성 LD50 i.p. in mice: 150 mg/kg (Brodersen, Kjaer)

anemonin C화학적 특성, 용도, 생산

개요

Anemonin (ANE) is a natural bioactive compound, an active compound of C. crassifolia, that regulates tyrosinase-related proteins and mRNAs in human melanocytes and inhibits melanin synthesis, making it a potential cosmetic ingredient. In addition, Anemonin has anti-aging properties, and it has been shown that ANE ameliorates human diploid fibroblast 2BS and IMR90 cellular senescence via the PARP1-NAD+-SIRT1 signalling pathway.

생물학적 활성

Anemonin is the dimerization product of the toxin protoanemonin and easily reacts with water to a dicarboxylic acid.

anemonin 준비 용품 및 원자재

원자재

준비 용품


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