1,2,4-트리아졸
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1,2,4-트리아졸 속성
- 녹는점
- 119-121 °C (lit.)
- 끓는 점
- 260 °C (lit.)
- 밀도
- 1.15 g/cm3 (130℃)
- 증기압
- 0.215Pa at 20℃
- 굴절률
- 1.4854 (estimate)
- 인화점
- 140 °C
- 저장 조건
- Store below +30°C.
- 용해도
- 547그램/리터
- 물리적 상태
- 결정성 분말 및 플레이크
- 산도 계수 (pKa)
- 2.27(at 20℃)
- 색상
- 하얀색
- 수소이온지수(pH)
- 8 (10g/l, H2O, 20℃)
- 수용성
- 1250g/L(20℃)
- Merck
- 14,9605
- BRN
- 104767
- InChIKey
- NSPMIYGKQJPBQR-UHFFFAOYSA-N
- LogP
- -0.76 at 25℃
- CAS 데이터베이스
- 288-88-0(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
위험품 표기 | Xn,Xi,C | ||
---|---|---|---|
위험 카페고리 넘버 | 22-36-63-34 | ||
안전지침서 | 36/37-45-36/37/39-27-26 | ||
WGK 독일 | 2 | ||
RTECS 번호 | XZ3806000 | ||
위험 참고 사항 | Irritant | ||
TSCA | Yes | ||
HS 번호 | 29339990 | ||
유해 물질 데이터 | 288-88-0(Hazardous Substances Data) | ||
독성 | LD50 orally in Rabbit: 1650 mg/kg LD50 dermal Rabbit 3129 - 4200 mg/kg | ||
기존화학 물질 | KE-34007 |
1,2,4-트리아졸 C화학적 특성, 용도, 생산
화학적 성질
white crystalline powder and flakes용도
1,2,4-Triazole is present in a large variety of fungicides as C14-demethylase-inhibitors. In addition they are used in synthetic chemical reactions such as the design and preparation of ghrelin receptor ligand antagonists, like JMV 2959.정의
1,2,4-triazole is a chemical substance with molecular formula C2H3N3, molecular weight 69.07 and CAS No. 288-88-0. Colorless acicular crystal, soluble in water and ethanol. 1H-1,2,4-triazole is a 1,2,4-triazole. It is a tautomer of a 3H-1,2,4-triazole and a 4H-1,2,4-triazole.Triazole is an aromatic five membered heterocyclic compound. Its unique structure is conducive to the formation of a variety of non covalent bonds and is easy to promote the binding of proteins, enzymes and receptors, thus showing a wide range of biological pharmacological activities, such as anticancer, antispasmodic, antibacterial, anti HIV. In particular, 1,2,3-triazole has strong thermal stability and acid-base stability, and is not sensitive to redox, hydrolysis and enzymatic degradation. It is often used as a pharmacodynamic group in drug synthesis.
Purification Methods
Crystallise 1,2,4-triazole from EtOH, H2O, EtOAc (m 120.5-121o), or EtOH/*C6H6. The hydrochloride has m 170o, and the picrate has m 163-164o (from H2O or CHCl3). [Barszcz et al. J Chem Soc, Dalton Trans 2025 1986]. [Beilstein 26 H 13, 26 II 6, 26 III/IV 35.]1,2,4-트리아졸 준비 용품 및 원자재
원자재
1,2-Diformylhydrazine
하이드라진 수화물
p-클로로벤즈알데히드
포름산암모늄
개미산
하이드라진, 모노수화물
포름산메틸
암모니아(가스)
Flutriafol
1H-1,2,4-Triazole, 1-chloro-
준비 용품
프로피콘아졸
적색 046 기초염료
1-[2-(4-CHLOROPHENYL)-1-(1-HYDROXY-1-PHENYLETHYL)ETHYL]-1,2,4-TRIAZOLE
1H-1,2,4-Triazole-1-carboximidamide hydrochloride
3,5-DIBROMO-1H-1,2,4-트라이아졸
아나스트로졸
1-(4-NITROBENZENESULFONYL)-1H-1,2,4-TRIAZOLE
플루코나졸
Triapenthenol
3-[(2,4-dihydro-2,4-dimethyl-3H-1,2,4-triazol-3-ylidene)hydrazono]-1-methyl-2-phenyl-3H-indolium chloride
파클로부트라졸
Basic Red 22
비테르탄올
1-(BETA-D-2-DEOXYRIBOFURANOSYL)-4-(1,2,4-TRIAZOL-1-YL)-5-METHYLPYRIMIDIN-2-ONE
3-chloro-6-(1H-1,2,4-triazol-1-yl)pyridazine(SALTDATA: FREE)
Benzaldehyde, 5-chloro-2-(1H-1,2,4-triazol-1-yl)-
1-(2-FLUORO-4-NITROPHENYL)-1H-1,2,4-TRIAZOLE
4-(1H-1,2,4-TRIAZOL-1-YLMETHYL)벤잘데하이드
1,2,4-트리아졸 공급 업체
글로벌( 905)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
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Shandong shuolan chemical co.ltd | +86-15725901680 +86-17865817560 |
coco@solarchem.cn | China | 3 | 58 |
Jiangxi Huihe Chemical Co., Ltd. | +86-19189228086 +8618858568638 |
wuzhouding@huihecrop.com | China | 886 | 58 |
Jiaxing Dongliang Pharmaceutical Technology Co.,Ltd. | +86-0573-84772883 +86-18905731109 |
hujidong@hailunchem.com | China | 7 | 58 |
Wuwei hailun New Material Technology Co., Ltd. | +86-0935-5322366 +86-13605736198 |
hailunchem@vip.163.com | China | 7 | 58 |
BTC pharm India | +918790379245 |
banny.janga@btcpharm.com | India | 1269 | 58 |
Jiangsu Guotai Guomian Trading Co. Ltd. | +86-512-58916079 +86-13601562190 |
pharmachem@gtgmt.com | China | 148 | 58 |
Junwee Chemical co., Ltd. | +86-571-85808636 +86-13958122542 |
sales@junweechem.com | China | 821 | 58 |
Shanghai Joiny Pharmaceutical Co.,LTD | +8613681955282 |
gyd@joiny-pharma.com | China | 229 | 58 |
Ouhuang Engineering Materials (Hubei) Co., Ltd | +8617702722807 |
admin@hbouhuang.com | China | 3001 | 58 |
Hebei Zhuanglai Chemical Trading Co.,Ltd | +8613343047651 |
admin@zlchemi.com | China | 2603 | 58 |
1,2,4-트리아졸 관련 검색:
아미트롤 메틸-1H-벤조트리아졸 1H-1,2,4-트리아졸-3-티올 벤조트리아졸 트리아졸 1-(4-클로로페녹시)-3,3-다이메틸-1-(1H-1,2,4-트리아졸-1-일)-2- 부타논 아미노-3-하이드라지노-5-머캅토-1,2,40트리아졸, 4-아미노-5-하이드라지노-1,2,4-트리아졸-3-티올 1,2,4-트리아졸
4-Amino-4H-1,2,4-triazole
1-CHLOROMETHYL-1H-1,2,4-TRIAZOLE
5-Methyl-1H-benzotriazole
1-Hydroxybenzotriazole hydrate
6-(1-Bromoethyl)-4-chloro-5-fluoropyrimidine
Voriconazole Impurity 53
Voriconazole
(2R,3S/2S,3R)-3-(4-Chloro-5-fluoro-6-pyrimidinyl)-2-(2,4-difluorophenyl)butan-2-ol hydrochloride
2-Chloro-2',4'-difluoroacetophenone
Pyrimidine, 4-bromo-6-(1-bromoethyl)-5-fluoro-