DICYCLOMINE HYDROCHLORIDE
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DICYCLOMINE HYDROCHLORIDE 속성
- 녹는점
- 164-166°C
- 저장 조건
- -20°C Freezer
- 용해도
- H2O: 50 mg/mL
- 물리적 상태
- 가루
- 색상
- 회백색
- BCS Class
- 2/4
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | Xn | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 22-36/37/38 | ||
| 안전지침서 | 26-36 | ||
| WGK 독일 | 3 | ||
| RTECS 번호 | DT7350000 | ||
| HS 번호 | 2922199695 | ||
| 독성 | LD50 orl-rat: 1290 mg/kg DRUGAY 6,317,82 |
DICYCLOMINE HYDROCHLORIDE C화학적 특성, 용도, 생산
개요
Dicyclomine is an M1 and M2 muscarinic acetylcholine receptor antagonist (Kis = 3.16 and 44.7 nM, respectively). It inhibits inositol phosphate accumulation induced by the non-selective acetylcholine agonist carbamoylcholine (carbachol; ) in guinea pig cortex (Ki = 12 nM; pA2 = 7.88). Dicyclomine (10 mg/kg, i.v.) inhibits potassium-induced contraction of ileum, colon, and duodenum in anesthetized rats by 21.85, 30.81, and 37.86%, respectively. Formulations containing dicyclomine have been used to treat functional and irritable bowel syndrome and to relieve muscle spasms in the gastrointestinal tract.화학적 성질
White Crystalline Powder용도
Dicyclomine Hydrochloride can be used as medication to treat gastric diseases.정의
ChEBI: The hydrochloride salt of dicyclomine. An anticholinergic, it is used to treat or prevent spasm in the muscles of the gastrointestinal tract, particularly that associated with irritable bowel syndrome.일반 설명
Dicyclomine hydrochloride,2-(diethylamino)ethyl bicyclohexyl-1-carboxylatehydrochloride (Bentyl), has some muscarinic receptorsubtype selectivity. It binds more firmly to M1 and M3 thanto M2 and M4 receptors.76Dicyclomine hydrochloride has one eighth of the neurotropicactivity of atropine and approximately twice themusculotropic activity of papaverine. This preparation, firstintroduced in 1950, has minimized the adverse effects associatedwith the atropine-type compounds.Clinical Use
Dicyclomine Hydrochloride is used for itsspasmolytic effect on various smooth muscle spasms, particularlythose associated with the GI tract. It is also usefulin dysmenorrhea, pylorospasm, and biliary dysfunction.Safety Profile
Poison by intravenous route.Moderately toxic by ingestion. Human systemic effects byingestion: rigidity, dyspnea, cyanosis. When heated todecomposition it emits very toxic fumes of HCl and NOx.DICYCLOMINE HYDROCHLORIDE 준비 용품 및 원자재
원자재
준비 용품
DICYCLOMINE HYDROCHLORIDE 공급 업체
글로벌( 107)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Antai Fine Chemical Technology Co.,Limited | 18503026267 |
info@antaichem.com | CHINA | 9641 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 19892 | 58 |
| AFINE CHEMICALS LIMITED | +86-0571-85134551 |
info@afinechem.com | China | 15396 | 58 |
| Alfa Chemistry | +1-5166625404 |
Info@alfa-chemistry.com | United States | 21317 | 58 |
| ZHEJIANG JIUZHOU CHEM CO., LTD | +86-0576225566889 +86-13454675544 |
admin@jiuzhou-chem.com；jamie@jiuzhou-chem.com；alice@jiuzhou-chem.com | China | 19949 | 58 |
| LEAPCHEM CO., LTD. | +86-852-30606658 |
market18@leapchem.com | China | 43348 | 58 |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +undefined18621343501 |
product@acmec-e.com | China | 33350 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 |
sales@aladdinsci.com | United States | 57511 | 58 |
| Suzhou ARTK Medchem Co., Ltd. | +8618168183658 |
sales1@artkmedchem.com | China | 39009 | 58 |
| Chemwill Asia Co.,Ltd. | 86-21-51086038 |
chemwill_asia@126.com | CHINA | 23931 | 58 |
DICYCLOMINE HYDROCHLORIDE 관련 검색:
바이시클로헥실 시클로헥실아세트산에틸에스테르
Aluminum hydroxide
Dapoxetine hydrochloride
Dicyclomine Hydrochloride Injection USP
DIHEXYVERINE, HYDROCHLORIDE
dicycloverine
METHYL CYCLOHEXANEACETATE
DICYCLOMINE HYDROCHLORIDE
Cyclohexylacetic acid
[1,1'-bicyclohexyl]-1-carboxylic acid
2-cyclohexylbutyric acid
ETHYL 2,2-DIETHYLBUTYRATE
1-METHYL-1-CYCLOHEXANECARBOXYLIC ACID
Isopropyl-cyclohexanecarboxylic acid