6-히드록시도파민 브롬화수소산염
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6-히드록시도파민 브롬화수소산염 속성
- 녹는점
- 216-220 °C(lit.)
- 저장 조건
- -20°C
- 용해도
- DMSO(약간 용해됨), 메탄올(약간 용해됨), 물(약간 용해됨)
- 물리적 상태
- 고체
- 물리적 상태
- 단단한 모양
- 색상
- 황갈색에서 갈색까지
- BRN
- 3713280
- 안정성
- 흡습성, 감광성
- InChIKey
- MLACDGUOKDOLGC-UHFFFAOYSA-N
- CAS 데이터베이스
- 636-00-0(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
6-히드록시도파민 브롬화수소산염 C화학적 특성, 용도, 생산
개요
6-OHDA is a catecholaminergic neurotoxin that has been used to induce dopaminergic lesions and parkinsonian symptoms as a model of Parkinson''s disease in rodents. It induces locomotor impairment in mice and loss of tyrosine hydroxylase-reactive neurons in mouse brain when administered into the substantia nigra, medial forebrain bundle (MFB), or striatum at doses of 9, 6, and 18 μg, respectively. Intracisternal administration of 6-OHDA (200 μg) decreases dopamine and norepinephrine levels in rat brain. It induces apoptosis in primary rat cortical cells and PC12 rat adrenal cells when used at a concentration of 50 μM. 6-OHDA (75 μM) activates caspase-3, -8, and -9 in a time-dependent manner and increases the level of intracellular reactive oxygen species (ROS) in PC12 cells and induces apoptosis in rat substantia nigra when stereotaxically injected into the right MFB.화학적 성질
beige to brown crystalline powder용도
6-Hydroxydopamine is a selective catecholaminergic neurotoxin. Studies show that 6-Hydroxydopamine can be used to create an animal model of Parkinson''s disease as it causes almost complete destruction of nigral dopaminergic neurons and their striatal terminals when injected into the substantia nigra of rats. 6-Hydroxydopamine induces apoptosis in PC12 cells.일반 설명
Solutions should be freshly prepared and protected from exposure to light.6-히드록시도파민 브롬화수소산염 준비 용품 및 원자재
원자재
준비 용품
6-히드록시도파민 브롬화수소산염 공급 업체
글로벌( 135)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 32715 | 60 |
| career henan chemical co | +86-0371-86658258 |
sales@coreychem.com | China | 29914 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 |
linda@hubeijusheng.com | CHINA | 22968 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 |
sales@chemdad.com | China | 39916 | 58 |
| Hebei Yanxi Chemical Co., Ltd. | +8617531190177 |
peter@yan-xi.com | China | 6011 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 19892 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 |
1026@dideu.com | China | 27843 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 |
sales@invivochem.cn | United States | 6393 | 58 |
| Nanjing Doge Biomedical Technology Co., Ltd | +86-25-58227606 +86-15305155328 |
sales@dogechemical.com | China | 4128 | 58 |
| LEAP CHEM CO., LTD. | +86-852-30606658 |
market18@leapchem.com | China | 24738 | 58 |
6-히드록시도파민 브롬화수소산염 관련 검색:
브롬화수소 3-히드록시티라민 하이드로브로마이드 1,2,4-벤젠트리올 6-히드록시도파민 브롬화수소산염
Formamidinium Bromide
Pyridinium tribromide
ETHYLAMINE HYDROBROMIDE
KEMPTIDE
6-HYDROXYDOPAMINE HYDROBROMIDE*W/ASCORBIC ACID
6-HYDROXYDOPAMINE HYDROBROMIDE WITH
2-(2-aminoethyl)phenol
BCMCM-CAGED 8-BR-CAMP, 2,5-HYDRATE
BCMCM-CAGED 8-BR-CGMP, TRIHYDRATE
oxidopamine