플로리드진 디하이드레이트
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플로리드진 디하이드레이트 속성
- 녹는점
- 113-114 °C(lit.)
- 알파
- -52 º (c=3, EtOH)
- 저장 조건
- Inert atmosphere,2-8°C
- 용해도
- Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
- optical activity
- [α]20/D 52°, c = 3 in ethanol
- BRN
- 66621
- CAS 데이터베이스
- 7061-54-3(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
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| 유해·위험 문구: |
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플로리드진 디하이드레이트 C화학적 특성, 용도, 생산
용도
Phloridzin dihydrate has been used as:- a Na+-glucose cotransport inhibitor to test its effect in lowering blood glucose
- a hexose carrier inhibitor to prevent glucose derivative 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose (2-NBDG) uptake in sycamore cells
- a non-specific sodium-glucose co-transporter 2 (SGLT2) inhibitor in embryonic cardiomyocyte cell line H9C2 to investigate its protective effect on Dox-induced cytotoxicity
Biochem/physiol Actions
Phloridzin is a glycoside present in the leaves and bark of apple. It is also present in peel and pulp of the apple fruit. Phloridzin belongs to the dihydrochalcones class of compounds. Lactase catabolizes phloridzin to phloretin and glucose in small intestine epithelial cells. Phloridzin is an antidiabetic agent and is equally bioavailable as phloretin.플로리드진 디하이드레이트 준비 용품 및 원자재
원자재
준비 용품
플로리드진 디하이드레이트 공급 업체
글로벌( 161)공급 업체
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