2-니트로페놀
|
|
2-니트로페놀 속성
- 녹는점
- 43-45 °C
- 끓는 점
- 214-216 °C
- 밀도
- 1.495
- 증기압
- 1 mm Hg ( 49.3 °C)
- 굴절률
- 1.5723
- 인화점
- 108 °C
- 저장 조건
- Store in dark!
- 용해도
- 2g/L(25°C)
- 산도 계수 (pKa)
- 7.17(at 25℃)
- 물리적 상태
- 액체
- 색상
- 맑은 연한 노란색
- pH 범위
- Colorless (5.0) to yellow (7.0)
- 수소이온지수(pH)
- 5.0～7.0
- 냄새
- 향기로운 냄새
- 수용성
- 2g/L(25℃)
- 감도
- Light Sensitive
- Merck
- 14,6619
- BRN
- 775403
- Henry's Law Constant
- At 20 °C: 11.1 at pH 8.1, 11.0 at pH 10.2, 8.9 at pH 11.9, 6.7 at pH 13.7 (wetted-wall column-UV, Zhang et al., 2003)
- 안정성
- 안정적인. 강염기, 강산화제와 호환되지 않습니다.
- 주요 응용
- High voltage capacitors, inks, energetic materials, corrosion inhibitors, fertilizer, food storage, enzyme assays, detecting microorganisms, immunotherapy, drugs
- LogP
- 1.77
- 해리상수
- 7.23 at 25℃
- CAS 데이터베이스
- 88-75-5(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | Xn,T,F | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 22-36/37/38-52/53-33-20/21/22-39/23/24/25-23/24/25-11 | ||
| 안전지침서 | 26-61-45-36/37-16-7-36-28 | ||
| 유엔번호(UN No.) | UN 1663 6.1/PG 3 | ||
| WGK 독일 | 2 | ||
| RTECS 번호 | SM2100000 | ||
| 자연 발화 온도 | 550 °C | ||
| TSCA | Yes | ||
| 위험 등급 | 6.1 | ||
| 포장분류 | III | ||
| HS 번호 | 29089000 | ||
| 유해 물질 데이터 | 88-75-5(Hazardous Substances Data) | ||
| 독성 | LD50 orally in mice, rats: 1.297, 2.828 g/kg, K. C. Back et al., Reclassification of Materials Listed as Transportation Health Hazards (TSA-20-72-3; PB214-270, 1972) | ||
| 기존화학 물질 | KE-26011 |
2-니트로페놀 C화학적 특성, 용도, 생산
화학적 성질
yellow crystalline solid용도
2-Nitrophenol is an intermediate in dyestuff production and a chemical indicator.정의
ChEBI: A member of the class of 2-nitrophenols that is phenol in which one of the hydrogens that is ortho to the hydroxy group has been replaced by a nitro group.생산 방법
2-Chloronitrobenzene in 8.5 % sodium hydroxide solution is heated gradually (exothermic) to 170 ℃ in an autoclave and held there under pressure for 8 h. The resulting solution is cooled and acidified to give the product 2-Nitrophenol in 95 % yield.일반 설명
Yellow solid. Sinks in and mixes slowly with water.공기와 물의 반응
Water insoluble.반응 프로필
2-Nitrophenol is a yellow, crystalline material, moderately toxic, low melting point (45° C). When heated to decomposition 2-Nitrophenol emits toxic fumes of oxides of nitrogen. In molten form violent reaction with strong alkali (85 % potassium hydroxide) [491 M, 1975, p. 342]. Reaction product with chlorosulfuric acid decomposes violently at room temperature [Vervalin, C. H., Hydrocarbon Proc., 1976, 55(9), p. 321].위험도
Toxic by ingestion.건강위험
Inhalation or ingestion causes headache, drowsiness, nausea, and blue color in lips, ears, and fingernails (cyanosis). Contact with eyes causes irritation. Can be absorbed through the intact skin to give same symptoms as for inhalation.화재위험
Special Hazards of Combustion Products: Toxic and irritating fumes of unburned material and oxides of nitrogen can form in fire.Purification Methods
Crystallise 2-nitrophenol from EtOH/water, water, EtOH, *benzene or MeOH/pet ether (b 70-90o). It can be steam distilled. Petrucci and Weygandt [Anal Chem 33 275 1961] crystallised it from hot water (twice), then EtOH (twice), followed by fractional crystallisation from the melt (twice), drying over CaCl2 in a vacuum desiccator and then in a drying pistol. The 4-nitrobenzoate had m 141o (from EtOH). [Beilstein 6 IV 1246.]2-니트로페놀 준비 용품 및 원자재
원자재
준비 용품
아니시딘
2,3-Dihydro-2,2-dimethyl-7-benzofuranol
3-아미노-4-하이드록시벤젠술폰 산
2-Amino-6-bromophenol
5-Methoxymethyl-2,3-pyridinedicarboxylic acid
C-(3,4-DIHYDRO-2H-BENZO[1,4]OXAZIN-3-YL)-메틸아민
밥타
카보퓨란
밥타,테트라나트륨염
8-Hydroxyquinaldine
2-아미노페놀
8-하이드록시퀴놀린
2-Nitrophenoxyacetic acid
2-(2-모르폴린-4-일레톡시)아닐린
2,6-다이나이트로페놀
2-NITROTHIOPHENOL
3-Nitrosalicylic acid