들이마신 경우,호흡이 어려운 경우 환자를 신선한 공기가 있는 곳으로 옮기고 호흡하기 편한 자세로 안정을 취하게 함
P321
(…) 처치를 하시오.
P333+P313
피부자극성 또는 홍반이 나타나면 의학적인 조치·조언를 구하시오.
P342+P311
호흡기 증상이 나타나면 의료기관(의사)의 진찰을 받으시오.
P363
다시 사용전 오염된 의류는 세척하시오.
P501
...에 내용물 / 용기를 폐기 하시오.
세프록사딘 C화학적 특성, 용도, 생산
개요
Cefroxadine was synthesized by Ciba-Geigy in 1972. A methoxyl group replaced the methyl group of cephradine at the 3 position of the cephem nucleus. Cefroxadine shows stronger activities than cephalexin, especially bactericidal and bacteriolytic activities, and it has better oral absorption that is less affected by a recent meal. Cefroxadine shows less renal toxicity than cephalexin in toxicological studies using animals.
용도
Antibacterial.
Antimicrobial activity
Cefroxadine is closely related to cefradine, the structure differing
only by the presence of a methoxy group replacing methyl at the C-3 position. The antimicrobial spectrum is identical
to that of cefradine and cefalexin. A dose of
1 g as film-coated tablets produced mean peak plasma levels
of 25 mg/L at 1 h. Absorption is depressed and delayed by
administration with food. The plasma elimination half-life is
0.8 h, rising to 40 h in end-stage renal failure and falling to
3.4 h during hemodialysis. Around 85% of an oral dose is
excreted unchanged in the urine. It is available in Japan.
