벤조페논
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벤조페논 속성
- 녹는점
- 47-51 °C (lit.)
- 끓는 점
- 305 °C (lit.)
- 밀도
- 1.11
- 증기 밀도
- 4.21 (vs air)
- 증기압
- 1 mm Hg ( 108 °C)
- FEMA
- 2134 | BENZOPHENONE
- 굴절률
- 1.5893
- 인화점
- >230 °F
- 저장 조건
- Store below +30°C.
- 용해도
- 에탄올: 용해성100mg/mL, 투명, 무색(80% 에탄올)
- 물리적 상태
- 결정질 분말 또는 플레이크
- 색상
- 흰색에서 황백색까지
- 냄새
- 독특한 냄새
- ?? ??
- 발사믹
- 수용성
- 불용성(25°C에서 <0.1g/100mL)
- JECFA Number
- 831
- Merck
- 14,1098
- BRN
- 1238185
- Dielectric constant
- 13.0(20℃)
- 안정성
- 안정적인. 강한 산화제, 강한 환원제와 호환되지 않습니다. 타기 쉬운.
- InChIKey
- RWCCWEUUXYIKHB-UHFFFAOYSA-N
- LogP
- 3.18 at 25℃
- CAS 데이터베이스
- 119-61-9(CAS DataBase Reference)
- IARC
- 2B (Vol. 101) 2013
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
위험품 표기 | Xi,N,Xn,F | ||
---|---|---|---|
위험 카페고리 넘버 | 36/37/38-52/53-50/53-67-65-62-51/53-48/20-11-40 | ||
안전지침서 | 26-61-37/39-29-60-36-62-36/37-33-16-9 | ||
유엔번호(UN No.) | UN 3077 9/PG 3 | ||
WGK 독일 | 2 | ||
RTECS 번호 | DI9950000 | ||
F 고인화성물질 | 10 | ||
TSCA | Yes | ||
위험 등급 | 9 | ||
포장분류 | III | ||
HS 번호 | 29143900 | ||
유해 물질 데이터 | 119-61-9(Hazardous Substances Data) | ||
독성 | LD50 orally in Rabbit: > 10000 mg/kg LD50 dermal Rabbit 3535 mg/kg | ||
기존화학 물질 | KE-02716 |
벤조페논 C화학적 특성, 용도, 생산
용도
1. Benzophenone 는 같은 잉크, 이미징, UV 경화 애플리케이션에서 초기자 사진 및 인쇄 산업에서 코팅 선택을 취소으로 사용할 수 있습니다. Benzophenone 손상 향기에서 자외선 (UV)을 방지 하 고 향수, 비누 등 제품 색상. 2. Benzophenone 포장 폴리머 또는 그 내용을 사진-저하를 막을 UV 차단 로 플라스틱 포장에 추가할 수 있습니다. 그것의 사용에는 명확한 유리 또는 플라스틱 (예: 피트 물 병)에 제품을 포장 하는 제조 업체 수 있습니다. 그것 없이, 불투명 또는 어두운 포장 필요한 것입니다. 3. 생물 학적 응용 프로그램에서 benzophenones 사용 되었습니다 광범위 하 게 파악 하 고 펩타이드-단백질 상호 작용 지도 photophysical 프로브로. 4. Benzophenones 제약 중간체, 화장품 향수 및 살충제로 사용할 수 있습니다.화학적 성질
Benzophenone is a combustible, white, crystalline solid with a rose-like odor. soluble in ethanol, ether, chloroform and other organic solvents and monomers, insoluble in water. It is a free radical photoinitiator, mainly used in free radical UV curing systems, such as coatings, inks, adhesives, etc. It can be prepared in several ways, for example, by Friedel–Crafts reaction of benzene and benzoyl chloride with aluminum chloride, or of benzene and carbon tetrachloride, and oxidation of diphenylmethane.출처
Benzophenone has been found in various fruits, including Vitis vinifera L., black tea, cherimoya (Annona cherimola), mountain papaya (Carica pubescens), and soursop (Annona muricata L.).용도
Benzophenone is used as a synthetic intermediate for manufacture of pharmaceuticals and agricultural chemicals. It is also used as a photoinitiator in UV-curable printing inks, as a fragrance in perfumes, as a flavor enhancer in foods. Benzophenone can be added as a UV-absorbing agent to plastics, lacquers, and coatings at concentrations of 2–8%.생산 방법
Benzophenone is commercially synthesized by the atmospheric oxidation of diphenylmethane using a catalyst of copper naphthenate. Alternatively, it can be produced by a Friedel–Crafts acylation of benzene using either benzoyl chloride or phosgene in the presence of aluminum chloride .정의
ChEBI: Benzophenone is the simplest member of the class of benzophenones, being formaldehyde in which both hydrogens are replaced by phenyl groups. It has a role as a photosensitizing agent and a plant metabolite.일반 설명
Benzophenone(119-61-9) appears as white solid with a flowery odor. May float or sink in water. It is a widely used building block in organic chemistry, being the parent diarylketone.공기와 물의 반응
Insoluble in water.반응 프로필
Ketones, such as Benzophenone, are reactive with many acids and bases liberating heat and flammable gases (e.g., H2). The amount of heat may be sufficient to start a fire in the unreacted portion of the ketone. Ketones react with reducing agents such as hydrides, alkali metals, and nitrides to produce flammable gas (H2) and heat. Ketones are incompatible with isocyanates, aldehydes, cyanides, peroxides, and anhydrides. They react violently with aldehydes, HNO3, HNO3 + H2O2, and HClO4. Benzophenone can react with oxidizing materials.건강위험
Ingestion causes gastrointestinal disturbances. Contact causes eye irritation and, if prolonged, irritation of skin.화재위험
Flash point data for Benzophenone are not available, but Benzophenone is probably combustible.색상 색인 번호
Unsubstituted benzophenone is largely used in chemical applications. It acts as a marker for photoallergy to ketoprofen.Safety Profile
Moderately toxic by ingestion andintraperitoneal routes. Combustible when heated.Incompatible with oxidizers. When heated todecomposition it emits acrid and irritating fumes.잠재적 노출
Benzophenone is used in UV curing of inks and coatings; as an intermediate; as an odor fixative in fragrances, flavoring, soaps; in the manufacture of pharmaceuticals and insecticides; in organic syntheses.Carcinogenicity
Lifetime dermal carcinogenicity studies in mice and rabbits did not show any tumor excess in the treated animals. Female Swiss mice and New Zealand White rabbits of both sexes were treated dermally with 0, 5, 25, or 50% of benzophenone (0.02 mL) twice a week for 120 or 180 weeks. Weekly examination of the rabbits did not reveal any reduction in survival or appearance of tumors. Mice treated with benzophenone did not show any excess in the number of tumor-bearing animals or in total number of tumors compared to untreated control animals. Although three skin tumors were observed in the benzophenone- treated mice (one case of squamous cell carcinoma and two cases of squamous cell papilloma), there were also three tumors (one carcinoma and toe papillomas) observed in the control animals.신진 대사
Benzophenone's main metabolic pathway in the rabbit is by reduction to benzhydrol, which is excreted conjugated with glucuronic acid(Williams, 1959).Solubility in organics
Insoluble in water and glycerin, slightly soluble in Propylene glycol, 6% soluble in alcohol, soluble inmost perfume oils.운송 방법
UN1224 Ketones, liquid, n.o.s., Hazard Class: 3; Labels: 3—Flammable liquid, Technical Name Required. UN3077 Environmentally hazardous substances, solid, n.o.s., Hazard class: 9; Labels: 9—Miscellaneous hazardous material, Technical Name Required.Purification Methods
Crystallise it from MeOH, EtOH, cyclohexane, *benzene or pet ether, then dry in a current of warm air and store it over BaO or P2O5. It is also purified by zone melting and by sublimation [Itoh J Phys Chem 89 3949 1985, Naguib et al. J Am Chem Soc 108 128 1986, Gorman & Rodgers J Am Chem Soc 108 5074 1986, Ohamoto & Teranishi J Am Chem Soc 108 6378 1986, Naguib et al. J Phys Chem 91 3033 1987]. [Beilstein 7 III 2048, 7 IV 1357.]비 호환성
Oxidizing materials, such as dichromates and permanganates.벤조페논 준비 용품 및 원자재
원자재
준비 용품
3-Azetidinecarboxylic acid
토레미펜
BENZP-디니트라이드-티오-케톤
벤조페논히드라존
탐프라민
Basic Blue 11
클로나제팜
1-N-Boc-3-하이드록시아제티딘
Nordazepam
3-Methyl-7-phenyl-6-oxa-3-azabicyclo[6.4.0]dodeca-8,10,12-triene
Fluotrimazol
벤조피나콜
Nizofenone
4-벤조일아세트아닐리드
1-AMINOCYCLOPROPANECARBONITRILE
3,3′-디니트로벤조페논
2-AMINOPENT-4-YNENITRILE
염산디페니돌
2-(알파-히드록시벤즈히드릴)부티로니트릴
알파-[1-(아미노메틸)프로필]벤즈히드릴알코올
2-Amino-5-nitrobenzophenone
4-Methoxytriphenylmethyl chloride
3-Bromobenzophenone
N-Phenylbenzohydroxamic acid
벤즈히드롤
7-HYDROXYFLAVONE
디페닐메타니민
벤조페논 공급 업체
글로벌( 886)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
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Across Biotech Jinan Co LTD | +8613031735486 |
frank@acrossbiotech.com | China | 105 | 58 |
Wuhan Biet Co., Ltd. | +8617320528784 |
min@biet.com.cn | China | 41 | 58 |
Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 |
sales@tnjchem.com | China | 34571 | 58 |
Shanghai Bojing Chemical Co.,Ltd. | +86-86-02137122233 +8613795318958 |
bj1@bj-chem.com | China | 298 | 55 |
Hebei Xinsheng New Material Technology Co., LTD. | +86-16632316109 |
xinshengkeji@xsmaterial.com | China | 1100 | 58 |
Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 |
info@fdachem.com | China | 19368 | 58 |
Hebei Jingbo New Material Technology Co., Ltd | +8619931165850 |
hbjbtech@163.com | China | 1000 | 58 |
Ouhuang Engineering Materials (Hubei) Co., Ltd | +8617702722807 |
admin@hbouhuang.com | China | 3001 | 58 |
Xiamen Wonderful Bio Technology Co., Ltd. | +8613043004613 |
Sara@xmwonderfulbio.com | China | 305 | 58 |
Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8617865335152 |
Mandy@hangyubiotech.com | China | 11013 | 58 |
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2,4-디플루오로벤조페논 2,7-디니트로-9-플루오레논 에스쿨레틴 9-플루오레논 2-플루오로-9-플루오레논
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Phenytoin Impurity 3
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