Oxytocin free acid

Oxytocin free acid 구조식 이미지
카스 번호:
24346-32-5
상품명:
Oxytocin free acid
동의어(영문):
OXYTOCIN;Gly-OH9-Oxytocin;OXYTOCIN (FREE ACID);CYS-TYR-ILE-GLN-ASN-CYS-PRO-LEU-GLY;H-CYS-TYR-ILE-GLN-ASN-CYS-PRO-LEU-GLY-OH;H-c[Cys-Tyr-Ile-Gln-Asn-Cys]-Pro-Leu-Gly-OH;H-CYS-TYR-ILE-GLN-ASN-CYS-PRO-LEU-GLY-OH USP/EP/BP;REF DUPL: H-c[Cys-Tyr-Ile-Gln-Asn-Cys]-Pro-Leu-Gly-OH;H-Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Leu-Gly-OH, (Disulfide bond);Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH2 (Disulfide bridge Cys1-Cys6)
CBNumber:
CB6111652
분자식:
C43H65N11O13S2
포뮬러 무게:
1008.17
MOL 파일:
24346-32-5.mol

Oxytocin free acid 속성

저장 조건
-15°C
수용성
Soluble in water to 1mg/ml
InChIKey
NFBCSRNZYJJWNB-IEIRLNIENA-N

안전

Oxytocin free acid C화학적 특성, 용도, 생산

개요

Oxytocin free acid (9-Deamidooxytocin) is an analog of oxytocin in which the glycinamide residue at position 9 in oxytocin has been replaced by a glycine residue. Oxytocin is a pleiotropic, peptide hormone with broad implications for general health, adaptation, development, reproduction, and social behavior.

용도

Free acid form of oxytocin, which is a hormone involved in many aspects of mammalian reproduction as well as other physiological processes such as bond pairing and cardiovascular homeostasis.

Biological Functions

Oxytocin is a cyclic 9-peptide that, like somatostatin, contains a ring that encompasses a disulfide bridge. Oxytocin has uterotonic action, contracting the muscles of the uterus during gestation, and plays an important role in milk ejection (not milk secretion, which is regulated by the peptide hormone prolactin) from the mammary ducts into the nipples. Exogenous oxytocin most commonly is used for induction of labor, wherein it improves uterine contractions to achieve early vaginal delivery for fetal or maternal reasons (e.g., preeclampsia, Rh factor problems, pregnancy that has exceeded 42 weeks). It also finds use following delivery of the placenta, because it promotes contraction and vasoconstriction and helps to control postpartum bleeding.

신진 대사

In humans, estimates of median plasma half-life of oxytocin range from 3.2 min after a single 2 U bolus injection to 4.8 min during a 500 mU min-1 infusion. Oxytocin is rapidly metabolised in the liver and kidneys, and also in the plasma during pregnancy by secreted oxytocinase (leucyl/cystinyl aminopeptidase), with some degree of metabolism also taking place in the mammary glands[1].

Oxytocin free acid 준비 용품 및 원자재

원자재

준비 용품


Oxytocin free acid 공급 업체

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