트리에틸렌 멜라민 C화학적 특성, 용도, 생산
용도
Triethylenemelamine (TEM) is a potent mutagen. It has
little, if any, industrial application. TEM is mainly used in
medicine as an antineoplastic agent and as a “positive control”
in many in vitro and in vivo mutagenicity assays.
일반 설명
Odorless white crystalline powder. Melting point 160°C, then rapidly polymerizes to a white solid. Almost immediate degradation at pH 3.0; rapid degradation at pH 5.0; and very little degradation at pH 7.5.
공기와 물의 반응
Soluble in water [Hawley]. Polymerizes readily with heat or moisture.
반응 프로필
TRIETHYLENEMELAMINE polymerizes readily with heat or moisture. Neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides.
화재위험
Flash point data for TRIETHYLENEMELAMINE are not available; however, TRIETHYLENEMELAMINE is probably combustible.
Safety Profile
Poison by ingestion,
intraperitoneal, intramuscular, intravenous,
and subcutaneous routes. Experimental
teratogenic and reproductive effects.
Questionable carcinogen with experimental
neoplastigenic and tumorigenic data. Human
mutation data reported. Can cause
gastrointestinal tract disturbances and bone
marrow depression. When heated to
decomposition it emits highly toxic fumes of
NOx. Used as an antineoplastic agent and as
an insect sterilant.
Carcinogenicity
In several older, limited studies,
triethylenemelamine reportedly produced tumors in mice by
the dermal and intraperitoneal routes and in rats by subcutaneous
and/or intramuscular administration. These data were
reviewed and evaluated by the IARC and judged as
“limited evidence of carcinogenicity in animals.” As a result
of this evaluation of the animal data and a lack of evidence of
carcinogenicity in humans, the IARC placed TEM in its
Group 3 category.
트리에틸렌 멜라민 준비 용품 및 원자재
원자재
준비 용품
