수퍼옥사이드 디스무타제

수퍼옥사이드 디스무타제
수퍼옥사이드 디스무타제 구조식 이미지
카스 번호:
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한글명:
수퍼옥사이드 디스무타제
동의어(한글):
수퍼옥사이드디스무타제;수퍼옥사이드디스무타제(SUPEROXIDEDISMUTASEFROMHUMANERYTHROCYTES);수퍼옥사이드디스뮤타아제;과산화물디스뮤타아제
상품명:
Superoxide dismutase
동의어(영문):
SOD;ORGOTEIN;SOD1;EC: 1.15.1.1;SOD-3;hrSOD;EC-SOD;Cuprein;rh-SOD1;Ontosein
CBNumber:
CB6401661
분자식:
NULL
포뮬러 무게:
0
MOL 파일:
Mol file

수퍼옥사이드 디스무타제 속성

저장 조건
-20°C
용해도
0.1mM EDTA를 함유한 0.05M 인산칼륨 완충액(pH 7.8)에 5mg/mL로 쉽게 용해됩니다.
물리적 상태
가루
색상
청회색
안전
  • 위험 및 안전 성명
  • 위험 및 사전주의 사항 (GHS)
위험품 표기 B
위험 카페고리 넘버 36/37/38
안전지침서 26-36-24/25-22-23
WGK 독일 3
F 고인화성물질 10-21
HS 번호 35079090
기존화학 물질 KE-32729
그림문자(GHS): GHS hazard pictograms
신호 어: Warning
유해·위험 문구:
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드
H315 피부에 자극을 일으킴 피부부식성 또는 자극성물질 구분 2 경고 GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 눈에 심한 자극을 일으킴 심한 눈 손상 또는 자극성 물질 구분 2A 경고 GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 호흡 자극성을 일으킬 수 있음 특정 표적장기 독성 - 1회 노출;호흡기계 자극 구분 3 경고 GHS hazard pictograms
예방조치문구:
P261 분진·흄·가스·미스트·증기·...·스프레이의 흡입을 피하시오.
P271 옥외 또는 환기가 잘 되는 곳에서만 취급하시오.
P280 보호장갑/보호의/보안경/안면보호구를 착용하시오.

수퍼옥사이드 디스무타제 MSDS


SOD

수퍼옥사이드 디스무타제 C화학적 특성, 용도, 생산

정의

Any of a type of antioxidant metalloenzymes that occur in aerobic and facultatitive bacteria and in eukarotes. They catalyze a reaction in which two molecules of the highly toxic, highly reactive, superoxide anion is converted into one molecule each of hydrogen peroxide and molecular oxygen.

benefits

Based on the metal cofactors present in the active sites, Superoxide dismutases (SODs) can be classified into four distinct groups: Copper-Zinc-SOD (Cu, Zn-SOD), Iron SOD (Fe-SOD), Manganese SOD (Mn-SOD), and Nickel SOD. The enzyme can serve as an anti-inflammatory agent and can also prevent precancerous cell changes. SOD is used in cosmetics and personal care products as an anti-aging ingredient and antioxidant due to its ability to reduce free radical damage to the skin, therefore preventing wrinkles, fine lines, and age spots, and it also helps with wound healing, softens scar tissue, protects against UV rays, and reduces other signs of aging. It has been reported that SOD has an important link in several human health problems including RBC-related disorders, cystic fibrosis (CF), postcholecystectomy pain syndrome, malignant breast disease, steroid-sensitive nephrotic syndrome, amyotrophic lateral sclerosis, neuronal apoptosis, AIDS, and cancer. In many animal models having myocardial ischemia-reperfusion injury, inflammation, cerebral ischemia-reperfusion injury, etc., SOD enzymes are found to be very effective. Furthermore, a strong association between the activity of SOD and Alzheimer's disease has been suggested by some researchers[1-2].

일반 설명

Superoxide dismutases are a group of low molecular weight metalloproteins present in all aerobic cells of plants, animals and micro-organisms. They provide protection against damaging reactions with the superoxide radical anion (O2-) by catalyzing its disproportionation into oxygen and hydrogen peroxide.

일반 설명

Superoxide dismutase (SOD) is the only antioxidant enzyme that scavenges the superoxide anion by converting this free radical to oxygen and hydrogen peroxide, thus preventing peroxynitrite production and further damage. Superoxide dismutase is extensively researched and used in anti-inflammatory, antitumor, radiation protection, and antisenility applications.

Purification Methods

The dismutase is purified by DEAE-Sepharose and copper chelate affinity chromatography. The preparation is homogeneous by SDS-PAGE, by analytical gel filtration chromatography and by isoelectric focusing.

수퍼옥사이드 디스무타제 준비 용품 및 원자재

원자재

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