Bufexamac is a specific inhibitor of class IIB histone deacetylases (HDAC6 and HDAC10). Bufexamac is a non-steroidal anti-inflammatory drug used topically as well as rectally. Formulations containing
Bufexamac is used by many patients with eczematous disorders as an alternative to topical corticosteroids.
정의
ChEBI: A hydroxamic acid derived from phenylacetamide in which the benzene moiety is substituted at C-4 by a butoxy group. It has anti-inflammatory, analgesic, and antipyretic properties.
World Health Organization (WHO)
Bufexamac, an analgesic and anti-inflammatory agent, was
introduced in 1974 for the topical treatment of a wide range of dermatoses. The
drug is widely marketed and the World Health Organization is not aware of
restrictive action having been taken elsewhere.
색상 색인 번호
Bufexamac is an arylacetic nonsteroidal anti-inflammatory
drug. It induces allergic contact dermatitis,
eczematous or erythema multiforme like type, and
even generalized eruptions like acute generalized
exanthematous pustulosis.
