Y 134

Y 134 구조식 이미지
카스 번호:
849662-80-2
상품명:
Y 134
동의어(영문):
Y 134;Y-134,Y134;[6-HYDROXY-2-(4-HYDROXYPHENYL)BENZO[B]THIEN-3-YL]-[4-[4-(1-METHYLETHYL)-1-PIPERAZINYL]PHENYL]METHANONE;Methanone, [6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thien-3-yl][4-[4-(1-methylethyl)-1-piperazinyl]phenyl]-
CBNumber:
CB82453417
분자식:
C28H28N2O3S
포뮬러 무게:
472.6
MOL 파일:
849662-80-2.mol

Y 134 속성

저장 조건
Desiccate at RT
용해도
Soluble to 100 mM in DMSO and to 100 mM in ethanol
물리적 상태
가루

안전

Y 134 C화학적 특성, 용도, 생산

용도

Y 134 is a SERM displaying selectivity for ERα over ERβ.

생물학적 활성

Selective estrogen receptor modulator (SERM) that displays selectivity for ER α over ER β (K i values are 0.09 and 11.31 nM respectively) and no cross-reactivity with mineralocorticoid, glucocorticoid, androgen and progesterone receptors. Acts as an agonist in the bone and antagonist in reproductive tissue. Suppresses estrogen-stimulated proliferation of ER-positive human breast cancer MCF-7 and T47D cells.

Y 134 준비 용품 및 원자재

원자재

준비 용품


Y 134 공급 업체

글로벌( 24)공급 업체
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