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Benzene,1,3,5-trimethyl-2-[(4-methylphenyl)sulfonyl]-

Benzene,1,3,5-trimethyl-2-[(4-methylphenyl)sulfonyl]- 구조식 이미지

카스 번호:: 5184-64-5

상품명:: Benzene,1,3,5-trimethyl-2-[(4-methylphenyl)sulfonyl]-

동의어(영문):: ESI-05;NSC 116966;ESI-05 (ESI05);ESI-05 (NSC 116966);ESI-05 >=98% (HPLC);MESITYL P-TOLYL SULFONE;1,3,5-trimethyl-2-tosylbenzene;1,3,5-Trimethyl-2-[(4-methylphenyl)sulfonyl]benzene;Benzene,1,3,5-trimethyl-2-[(4-methylphenyl)sulfonyl]-;Diacylglycerol acyltransferase,diabetes,Inhibitor,inhibit,Intracranial hemorrhage (ICH),Acyltransferase,cAMP,acyl-CoA:cholesterol acyltransferase,NSC116966,insulin secretion,mono- acylglycerol acyltransferase,exchange proteins directly activated by cAMP 2 (EPAC2),neurological disorders,NSC-116966,GEF,Diglyceride acyltransferase,ESI 05,ESI-05,ESI05

CBNumber:: CB83290819

분자식:: C16H18O2S

포뮬러 무게:: 274.38

MOL 파일:: 5184-64-5.mol

MSDS 파일:: SDS

속성

안전

용도

공급 업체 27

Benzene,1,3,5-trimethyl-2-[(4-methylphenyl)sulfonyl]- 속성

녹는점: 119-120 °C

끓는 점: 426.7±45.0 °C(Predicted)

밀도: 1.129±0.06 g/cm3(Predicted)

저장 조건: room temp

용해도: DMSO: 용해될 수 있다

물리적 상태: 가루

색상: 흰색에서 베이지색

안전

Benzene,1,3,5-trimethyl-2-[(4-methylphenyl)sulfonyl]- C화학적 특성, 용도, 생산

용도

ESI-05 has been used to study the effect of protein exchange directly activated by cAMP 2 on traumatic brain injury.

Biochem/physiol Actions

ESI-05 is a selective inhibitor against cAMP-regulated guanine nucleotide exhange factor (GEF) EPAC2 (Exchange factor directly activated by cAMP 2) activation by targeting an EPAC2-specific allosteric site at the interface of the two cAMP-binding domains. ESI-05 inhibits EAPC2, but not EPAC1 or PKA, activation by cAMP in a highly potent (IC50 = 430 nM; 25 μM cAMP) and cAMP-competitive manner in cell-free assays, and suppresses cAMP analog 007-AM-induced cellular Rap1 activation in EPAC2-, but not EPAC1-, expressing HEK293 transfectants.

Benzene,1,3,5-trimethyl-2-[(4-methylphenyl)sulfonyl]- 준비 용품 및 원자재

원자재

준비 용품

Benzene,1,3,5-trimethyl-2-[(4-methylphenyl)sulfonyl]- 공급 업체

글로벌( 27)공급 업체

공급자	전화	이메일	국가	제품 수	이점
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6393	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	57511	58
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51471	80
BOC Sciences	16314854226	info@bocsci.com	United States	9926	65
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9709	58
Tianjin Kailiqi Biotechnology Co., Ltd.	15076683720	klq@cw-bio.com	China	3500	55
Beijing Solarbio Science & Tecnology Co., Ltd.	010-50973130 4009686088	3193328036@qq.com	China	29796	68
DC Chemicals	021-58447131 13564518121	sales@dcchemicals.com	China	9414	58
Wuxi Kehua Biological Technology Co., Ltd.	0510-0510-86838766	2258830676@qq.com	China	3834	58