2,3-Lutidine
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2,3-Lutidine 속성
- 녹는점
- -15 °C (lit.)
- 끓는 점
- 162-163 °C (lit.)
- 밀도
- 0.945 g/mL at 25 °C (lit.)
- 굴절률
- n
20/D 1.508(lit.)
- 인화점
- 122 °F
- 저장 조건
- Inert atmosphere,Room Temperature
- 물리적 상태
- 액체
- 산도 계수 (pKa)
- 6.57(at 25℃)
- 색상
- 무색투명~미황색
- 수용성
- 95g/L(26℃)
- BRN
- 106418
- InChIKey
- HPYNZHMRTTWQTB-UHFFFAOYSA-N
- SMILES
- CC1=C(N=CC=C1)C
- LogP
- 1.638 (est)
- CAS 데이터베이스
- 583-61-9(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | Xn,F,Xi | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 10-22-37/38-41-20/21/22-36/37/38 | ||
| 안전지침서 | 16-26-39-36/37-36/37/39 | ||
| 유엔번호(UN No.) | UN 1993 3/PG 3 | ||
| WGK 독일 | 3 | ||
| TSCA | Yes | ||
| 위험 등급 | 6.1 | ||
| 포장분류 | II | ||
| HS 번호 | 29333990 |
2,3-Lutidine C화학적 특성, 용도, 생산
화학적 성질
clear colorless to slightly yellow liquid용도
2,3-Lutidine is a lansoprazole intermediates. It is used as pharmaceutical intermediate.정의
LOTUS: 2,3-Lutidine is a natural product found in Nicotiana tabacum with data available.Purification Methods
Steam distil it from a solution containing about 1.2 equivalents of 20% H2SO4, until ca 10% of the base has been carried over with the non-basic impurities. The acidic solution is then made alkaline, and the base is separated, dried over NaOH or BaO, and fractionally distilled. The distilled lutidine is converted to its urea complex by stirring 100g with 40g of urea in 75mL of H2O, cooling to 5o, filtering at the pump, and washing with 75mL of H2O. The complex, dissolved in 300mL of H2O, is steam distilled until the distillate gives no turbidity with a little solid NaOH. The distillate is then treated with excess solid NaOH, and the upper layer is removed: the aqueous layer is then extracted with diethyl ether. The upper layer and the ether extract are combined, dried (K2CO3), and distilled through a short column. Final purification is by fractional crystallisation using partial freezing. The picrate crystallises from EtOH with m 187-188o. [Kyte et al. J Chem Soc 4454 1960, Beilstein 20 H 243, 20 II 159, 20 III/IV 2765, 20/6 V 15.]2,3-Lutidine 준비 용품 및 원자재
원자재
2,3,4-trimethylpyridine
Pyridine, 1,2,3,4-tetrahydro-5,6-dimethyl-
(2-Methylpyridin-3-yl)methyl acetate
Ethanone, 1-(1-methyl-3-piperidinyl)- (9CI)
2,3,6-TRIMETHYLPYRIDINE
(2-METHYL-PYRIDIN-3-YL)-METHANOL
에틸피리딘-3
Ethyl 2-methylnicotinate
준비 용품
2,3-DIMETHYL-PYRIDIN-4-YLAMINE
3-METHYL-2-PYRIDINECARBOXALDEHYDE
2-Chloromethyl-3-methyl-4-(3-methoxypropoxy)pyridine hydrochloride
2-HYDROXYMETHYL-3-METHYLPYRIDINE
란소프라졸
4-Nitro-2,3-lutidine-N-oxide
2-HYDROXYMETHYL-4-METHOXYPROPOXY-3-METHYLPYRIDINE
4-Chloro-2,3-dimethylpyridine 1-oxide
2-Chloromethyl-3-methyl-4-(2,2,2-trifluoroethoxy)pyridine hydrochloride
2,3-Dimethylpyridine-N-oxide
2,6-루티딘
피리딘
2,3-Lutidine 공급 업체
글로벌( 397)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 |
sales@hbmojin.com | China | 12468 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29797 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21689 | 55 |
| Jiangsu Zhongbang Pharmaceutical Co., Ltd. | 025-87151996 |
zbsales@chinaredsun.com | CHINA | 32 | 55 |
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 |
fandachem@gmail.com | China | 9341 | 55 |
| career henan chemical co | +86-0371-86658258 |
sales@coreychem.com | China | 29914 | 58 |
| NINGBO INNO PHARMCHEM CO., LTD. | 13867897135 |
sales@nbinno.com | CHINA | 925 | 58 |
| Zhejiang ZETian Fine Chemicals Co. LTD | 18957127338 |
stella@zetchem.com | China | 2141 | 58 |
| Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 |
alice@crovellbio.com | China | 8829 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 |
linda@hubeijusheng.com | CHINA | 22968 | 58 |