2-Methylsuccinic acid

2-Methylsuccinic acid 속성

2-Methylsuccinic acid MSDS

2-Methylsuccinic acid

2-Methylsuccinic acid C화학적 특성, 용도, 생산

개요

Methylsuccinic acid is a normal metabolite found in human fluids and is an intermediate metabolite in the breakdown of fatty acids. Increased urinary levels of methylsuccinic acid (together with ethylmalonic acid) are the main biochemical measurable features in ethylmalonic encephalopathy.

화학적 성질

white to beige crystalline powder

용도

Methylsuccinic acid is used as a flux material and an important dyestuff intermediate. It is also used as an intermediate in medicine and pharmaceuticals.

제조 방법

A common method employed for the synthesis of alkanedioic acids involves the oxidation of lactone derivatives. However, in the case of y-butyrolactones, the oxidations have proven particularly challenging due to the stability of the five-membered lactones. A successful approach to this type of oxidative preparation involves the carboxylation of γ-butyrolactone using carbon monoxide and hydrogen fluoride-antimony(V) fluoride superacid containing an excess of antimony(V) fluoride to afford 2-methylsuccinic acid.

Synthesis of 2-Methylsuccinic Acid from y-Butyrolactone

정의

ChEBI: 2-methylbutanedioic acid is a dicarboxylic acid that is butanedioic acid substituted at position 2 by a methyl group. It is a conjugate acid of a methylsuccinate.

Origin

2-Methylsuccinic acid is a natural product found in African aloe vera.

일반 설명

White or yellowish crystals or beige powder.

공기와 물의 반응

Water soluble.

건강위험

ACUTE/CHRONIC HAZARDS: 2-Methylsuccinic acid may be harmful by inhalation, ingestion or skin absorption. When heated to decomposition it emits toxic fumes of carbon monoxide and carbon dioxide.

화재위험

Flash point data for 2-Methylsuccinic acid are not available; however, 2-Methylsuccinic acid is probably combustible.

응급 처치

Eyes: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.
Skin: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment.
Inhalation: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used; if not available, use a level of protection greater than or equal to that advised under Protective Clothing.
Ingestion: DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. Be prepared to transport the victim to a hospital if advised by a physician. If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport the victim to a hospital.

Purification Methods

Crystallise the acid from water. [Beilstein 2 IV 1948.]

2-Methylsuccinic acid 준비 용품 및 원자재

원자재

준비 용품

2-Methylsuccinic acid 공급 업체

공급자	전화	이메일	국가	제품 수	이점
Beijing Risun Science and Technology Limited	+8619801193650	xykj@risun.com	China	13	58
Shanghai Bojing Chemical Co.,Ltd.	+86-86-02137122233 +8613795318958	bj1@bj-chem.com	China	298	55
Shanghai Zheyan Biotech Co., Ltd.	18017610038	zheyansh@163.com	CHINA	3620	58
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Accela ChemBio Inc.	(+1)-858-699-3322	info@accelachem.com	United States	19965	58
Xiamen AmoyChem Co., Ltd	+86-592-6051114 +8618959220845	sales@amoychem.com	China	6387	58
Chongqing Chemdad Co., Ltd	+86-023-61398051 +8613650506873	sales@chemdad.com	China	39916	58
Nanjing jinheyou Trading Co., Ltd.	15705188088	admin@jheyou.com	CHINA	1268	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49391	58
Zhengzhou Alfa Chemical Co.,Ltd	+8618530059196	sale04@alfachem.cn	China	12803	58

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