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ChemicalBook >> CAS DataBase List >>Bupropion

Bupropion suppliers

Bupropion

CAS:
34911-55-2
MF:
C13H18ClNO
MW:
239.74

Properties

Melting point:
233-234°C
Boiling point:
bp.005 52°
Density 
1.066±0.06 g/cm3(Predicted)
solubility 
ethanol: 193 mg/mL solutions may be stored for several days at 4 °C.
form 
solid
pka
pKa 7.0 (Uncertain)
color 
white
BCS Class
1

Safety Information

Hazard Codes 
Xn
Risk Statements 
22
Safety Statements 
36
WGK Germany 
3
RTECS 
UG8858000
HazardClass 
IRRITANT

Use

Bupropion hydrochloride, an aminoketone structurally unrelated to tricyclics or tetracyclics, is a dopamine uptake blocker with antidepressant activity. Its clinical efficacy is reportedly comparable to that of amitriptyline, yet unlike most conventional antidepressants, bupropion hydrochloride is not associated with orthostatic hypotension or other cardiovascular side-effects.

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