Brimonidine manufacturers and suppliers

Brimonidine suppliers

Properties

Melting point:: 207.5 °C

Boiling point:: 432.6±55.0 °C(Predicted)

Density: 1.82±0.1 g/cm3(Predicted)

storage temp.: Keep in dark place,Sealed in dry,2-8°C

solubility: 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: <0.8 mg/mL

form: powder to crystal

pka: 7.69±0.10(Predicted)

color: Light yellow to Amber to Dark green

Merck: 14,1375

Safety Information

Symbol(GHS): GHS06

Signal word: Danger

Hazard statements: H301

Precautionary statements: P301+P310

Hazard Codes: T

Risk Statements: 25-36/37/38

Safety Statements: 26-36-45

RIDADR: UN 2811 6.1/PG 3

WGK Germany: -

RTECS: VD1200000

HazardClass: 6.1

PackingGroup: Ⅲ

HS Code: 29332900

Use

Launched in the US for open-angle glaucoma and ocular hypertension, brimonidine is a relatively selective and potent α2a,-adrenergic agonist with low affinity for the imidazoline l1 receptor. Topical application reduces intraocular pressure. This bypasses any central hypotensive effects at the l1 receptor (which can also give rise to a decrease in blood pressure and heart rate) if given systemically, since topical application results in low plasma levels concomitant with rapid systemic elimination. Brimonidine can be prepared in a four-step sequence from 4-nitrophenylenediamine.

You can find Brimonidine suppliers, manufacturers, and distributors from countries such as China, United States and the India here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.