Phthalazinone pyrazole
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- $60 - $1900
- Product name: Phthalazinone pyrazole
- CAS: 880487-62-7
- MF: C18H15N5O
- MW: 317.34
- EINECS:
- MDL Number:MFCD28399120
- Synonyms:Phthalazinone pyrazole;Phthalazinone pyrazole Exclusive;4-[(5-methyl-1H-pyrazol-3-yl)amino]-2-phenylphthalazin-1-one;1(2H)-Phthalazinone, 4-[(5-methyl-1H-pyrazol-3-yl)amino]-2-phenyl-;4-[(5-Methyl-1H-pyrazol-3-yl)amino]-2-phenyl-2H-phthalazin-1-one;Phthalazinone pyrazole,inhibit,human embryonic stem cells,Aurora Kinase,hepatocyte-like cell,Inhibitor,HLCs,Aurora-A kinase,EMT,apoptosis,tumor growth,oral,epithelial-mesenchymal transition
12 prices
Selected condition：
Brand
- aablocks
- ApexBio Technology
- Cayman Chemical
- DC Chemicals
Package
- 002
- 1mg
- 003
- 5mg
- 10mg
- 001
- Manufactureraablocks
- Product numberAA00GT8T
- Product descriptionPhthalazinonepyrazole ≥98%
- Packaging1mg
- Price$119
- Updated2021-12-16
- Buy
- Manufactureraablocks
- Product numberAA00GT8T
- Product descriptionPhthalazinonepyrazole ≥98%
- Packaging5mg
- Price$360
- Updated2021-12-16
- Buy
- Manufactureraablocks
- Product numberAA00GT8T
- Product descriptionPhthalazinonepyrazole ≥98%
- Packaging10mg
- Price$600
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC3823
- Product descriptionPhthalazinonepyrazole
- Packaging1mg
- Price$60
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC3823
- Product descriptionPhthalazinonepyrazole
- Packaging5mg
- Price$269
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC3823
- Product descriptionPhthalazinonepyrazole
- Packaging10mg
- Price$477
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number10735
- Product descriptionPhthalazinone pyrazole ≥98%
- Packaging1mg
- Price$68
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number10735
- Product descriptionPhthalazinone pyrazole ≥98%
- Packaging5mg
- Price$302
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number10735
- Product descriptionPhthalazinone pyrazole ≥98%
- Packaging10mg
- Price$535
- Updated2024-03-01
- Buy
- ManufacturerDC Chemicals
- Product number027673
- Product descriptionPhthalazinonepyrazole
- Packaging001
- Price$550
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product number027673
- Product descriptionPhthalazinonepyrazole
- Packaging002
- Price$950
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product number027673
- Product descriptionPhthalazinonepyrazole
- Packaging003
- Price$1900
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00GT8T | Phthalazinonepyrazole ≥98% | 1mg | $119 | 2021-12-16 | Buy |
| aablocks | AA00GT8T | Phthalazinonepyrazole ≥98% | 5mg | $360 | 2021-12-16 | Buy |
| aablocks | AA00GT8T | Phthalazinonepyrazole ≥98% | 10mg | $600 | 2021-12-16 | Buy |
| ApexBio Technology | C3823 | Phthalazinonepyrazole | 1mg | $60 | 2021-12-16 | Buy |
| ApexBio Technology | C3823 | Phthalazinonepyrazole | 5mg | $269 | 2021-12-16 | Buy |
| ApexBio Technology | C3823 | Phthalazinonepyrazole | 10mg | $477 | 2021-12-16 | Buy |
| Cayman Chemical | 10735 | Phthalazinone pyrazole ≥98% | 1mg | $68 | 2024-03-01 | Buy |
| Cayman Chemical | 10735 | Phthalazinone pyrazole ≥98% | 5mg | $302 | 2024-03-01 | Buy |
| Cayman Chemical | 10735 | Phthalazinone pyrazole ≥98% | 10mg | $535 | 2024-03-01 | Buy |
| DC Chemicals | 027673 | Phthalazinonepyrazole | 001 | $550 | 2021-12-16 | Buy |
| DC Chemicals | 027673 | Phthalazinonepyrazole | 002 | $950 | 2021-12-16 | Buy |
| DC Chemicals | 027673 | Phthalazinonepyrazole | 003 | $1900 | 2021-12-16 | Buy |
Properties
Boiling point :557.7±52.0 °C(Predicted)
Density :1.35±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :insoluble in EtOH; insoluble in H2O; ≥7.14 mg/mL in DMSO
form :crystalline solid
pka :13.83±0.10(Predicted)
Density :1.35±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :insoluble in EtOH; insoluble in H2O; ≥7.14 mg/mL in DMSO
form :crystalline solid
pka :13.83±0.10(Predicted)
Safety Information
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Description
Three Aurora kinases, A-C, are involved in phosphorylation events that are critical for the completion of mitosis. Aurora A, involved in centrosomal assembly and acentrosomal spindle assembly, is overexpressed in many tumors. Phthalazinone pyrazole is a potent inhibitor of Aurora A kinase (IC50 = 31 nM). It does not inhibit Aurora B kinase at doses up to 100 μM. Phthalazinone pyrazole inhibits the proliferation of HCT116, Colo205, and MCF-7 cells (IC50 = 7.8, 2.9, and 1.6 μM, respectively).Suppliers and manufacturers
ATK CHEMICAL COMPANY LIMITED
TargetMol Chemicals Inc.
Hangzhou MolCore BioPharmatech Co.,Ltd.
Nantong HI-FUTURE Biology Co., Ltd.
ShangHai Biochempartner Co.,Ltd
Shanghai Yu Ben Biotechnology Co., Ltd.
DC Chemicals
Changzhou Chenhong Biotechnology Co., Ltd.
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
ShangHai ChuanQian Chemcial Technique Centre