| | 66164-07-6 Basic information More.. |
| Product Name: | DESMETHYL LOPERAMIDE | | Synonyms: | DESMETHYL LOPERAMIDE;4-(4-Chlorophenyl)-4-hydroxy-N-methyl-a,a-diphenyl-1-piperidinebutanamide;N-Desmethyl Loperamide;R 20905;Desmethyl loperamide HCl;Desmethylloperamide D5;4-(4-Chlorophenyl)-4-hydroxy-N-Methyl-α,α-diphenyl-1-piperidinebutanaMide;1-Piperidinebutanamide, 4-(4-chlorophenyl)-4-hydroxy-N-methyl-α,α-diphenyl- | | CAS: | 66164-07-6 | | MF: | C28H31ClN2O2 | | MW: | 463.01 | | EINECS: | | | Mol File: | 66164-07-6.mol |  |
Use
Loperamide is an opiate which potently and selectively activates μ opioid receptors (Ki = 0.16 nM) exclusively in the periphery. N-Desmethyl-loperamide (dLop) is a major metabolite of loperamide. Like loperamide, dLop is a substrate of the ATP-dependent efflux transporter, P-glycoprotein. As a result, both the parent compound and the metabolite display restricted passage through the blood-brain barrier. dLop in biological samples can be analyzed by a variety of methods.
- DESMETHYL LOPERAMIDE
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- US $0.00 / gram
- 2022-02-18
- CAS:66164-07-6
- Min. Order: 1gram
- Purity: 99%
- Supply Ability: 10kg
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66164-07-6
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