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DESMETHYL LOPERAMIDE

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DESMETHYL LOPERAMIDE Suppliers list
Company Name: Hubei Jusheng Technology Co.,Ltd.
Tel: 18871490254
Email: linda@hubeijusheng.com
Products Intro: Product Name:N-Desmethyl Loperamide
CAS:66164-07-6
Purity:99% Package:5KG;1KG Remarks:C28H31ClN2O2
Company Name: Finetech Industry Limited
Tel: +86-27-87465837 +8618971612321
Email: info@finetechnology-ind.com
Products Intro: Product Name:N-Desmethyl Loperamide
CAS:66164-07-6
Purity:98% Package:1g,10g,25g,500g,1kg Remarks:N/A
Company Name: Zhejiang J&C Biological Technology Co.,Limited
Tel: +1-2135480471 +1-2135480471
Email: sales@sarms4muscle.com
Products Intro: Product Name:DESMETHYL LOPERAMIDE
CAS:66164-07-6
Purity:99% Package:1gram;USD
Company Name: sgtlifesciences pvt ltd
Tel: +8617013299288
Email: dj@sgtlifesciences.com
Products Intro: Product Name:Desmethyl Loperamide
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354
Email: support@targetmol.com
Products Intro: Product Name:N-Desmethyl Loperamide；dLop;R-20905;R 20905;R20905
CAS:66164-07-6
Package:100 mg；500 mg Remarks:REAGENT;FOR LABORATORY USE ONLY

DESMETHYL LOPERAMIDE manufacturers

  • DESMETHYL LOPERAMIDE
  • DESMETHYL LOPERAMIDE pictures
  • $0.00 / 1gram
  • 2022-02-18
  • CAS:66164-07-6
  • Min. Order: 1gram
  • Purity: 99%
  • Supply Ability: 10kg
DESMETHYL LOPERAMIDE Basic information
Product Name:DESMETHYL LOPERAMIDE
Synonyms:DESMETHYL LOPERAMIDE;4-(4-Chlorophenyl)-4-hydroxy-N-methyl-a,a-diphenyl-1-piperidinebutanamide;N-Desmethyl Loperamide;R 20905;Desmethyl loperamide HCl;Desmethylloperamide D5;4-(4-Chlorophenyl)-4-hydroxy-N-Methyl-α,α-diphenyl-1-piperidinebutanaMide;1-Piperidinebutanamide, 4-(4-chlorophenyl)-4-hydroxy-N-methyl-α,α-diphenyl-
CAS:66164-07-6
MF:C28H31ClN2O2
MW:463.01
EINECS:
Product Categories:Amines;Heterocycles;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals
Mol File:66164-07-6.mol
DESMETHYL LOPERAMIDE Structure
DESMETHYL LOPERAMIDE Chemical Properties
Melting point 219-221?C
Boiling point 678.3±55.0 °C(Predicted)
density 1?+-.0.06 g/cm3(Predicted)
storage temp. -20°C Freezer
solubility DMF: 2 mg/ml; DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml; DMSO: 1 mg/ml
form A crystalline solid
pka13.85±0.20(Predicted)
Safety Information
HS Code 9999999999
MSDS Information
DESMETHYL LOPERAMIDE Usage And Synthesis
Chemical PropertiesOff-White Solid
UsesA metabolite of Loperamide; a new and improved PET radiotracer for imaging P-gp function
UsesLoperamide is an opiate which potently and selectively activates μ opioid receptors (Ki = 0.16 nM) exclusively in the periphery. N-Desmethyl-loperamide (dLop) is a major metabolite of loperamide. Like loperamide, dLop is a substrate of the ATP-dependent efflux transporter, P-glycoprotein. As a result, both the parent compound and the metabolite display restricted passage through the blood-brain barrier. dLop in biological samples can be analyzed by a variety of methods.
DefinitionChEBI: A monocarboxylic acid amide that is the methylamide of 4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-2,2-diphenylbutanoic acid.
DESMETHYL LOPERAMIDE Preparation Products And Raw materials
Tag:DESMETHYL LOPERAMIDE(66164-07-6) Related Product Information
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