| | 439571-48-9 Basic information More.. |
| Product Name: | NDT 9513727 | | Synonyms: | NDT 9513727;N,N-Bis(1,3-benzodioxol-5-ylmethyl)-1-butyl-2,4-diphenyl-1H-Imidazole-5-methanamine;1H-Imidazole-5-methanamine, N,N-bis(1,3-benzodioxol-5-ylmethyl)-1-butyl-2,4-diphenyl- | | CAS: | 439571-48-9 | | MF: | C36H35N3O4 | | MW: | 573.68 | | EINECS: | | | Mol File: | 439571-48-9.mol |  |
Use
NDT 9513727 is a selective, and potent inverse agonist of the human C5aR. NDT 9513727 has been shown to effectively inhibit C5a-induced neutropenia in gerbil and cynomolgus macaque in vivo. These results suggest that NDT 9513727 is a promising candidate for the treatment of human inflammatory diseases.
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439571-48-9
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