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Ethyl Trifluoroacetoacetate

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Ethyl Trifluoroacetoacetate Suppliers list
Company Name: Shanghai Likang New Materials Co., Limited
Tel: +86-16631818819 +86-17736933208
Email: 3684455296@qq.com
Products Intro: Cas:372-31-6
ProductName:Ethyl trifluoroacetoacetate
Purity: 99% | Package: 100KG;10KG;5KG;1KG
Company Name: Hubeicowardchemical  
Tel: 027-83295551 13317178958
Email: 385079137@qq.com
Products Intro: Cas:372-31-6
ProductName:Ethyl trifluoroacetoacetate
Purity: 99
Company Name: Wuhan Xiju Biotechnology Co., Ltd  
Tel: 13001802035
Email: 2307019145@qq.com
Products Intro: Cas:372-31-6
ProductName:Ethyl trifluoroacetoacetate
Purity: 99% | Package: 25kg/RMB 88
Company Name: Wuhan canos Technology Co., Ltd  
Tel: 153-37111468; 15337111468
Email: 3564510578@qq.com
Products Intro: Cas:372-31-6
ProductName:Ethyl trifluoroacetoacetate
Purity: 99% | Package: 200kg;25kg;5kg
Company Name: GIHI CHEMICALS CO.,LIMITED
Tel: +8618058761490
Email: info@gihichemicals.com
Products Intro: Cas:372-31-6
ProductName:Ethyl trifluoroacetoacetate
Purity: 99 | Package: 5KG;1KG,25kg

Ethyl Trifluoroacetoacetate manufacturers
Ethyl Trifluoroacetoacetate Basic information
Product Name:Ethyl Trifluoroacetoacetate
Synonyms:Ethyl 4,4,4-trifluoro-3-oxobutyrate;(Trifluoroacetyl)acetic acid ethyl ester;2-(Trifluoroacetyl)acetic acid ethyl ester;3-Oxo-4,4,4-trifluorobutanoic acid ethyl ester;4,4,4-Trifluoro-3-oxobutyric acid ethyl ester;Trifluoroacetylacetic acid ethyl ester;Ethyl 4,4,4-trifluoroacetoacetate 98%;Ethyl4,4,4-trifluoroacetoacetate98%
CAS:372-31-6
MF:C6H7F3O3
MW:184.11
EINECS:206-750-7
Product Categories:Fluorinated Building Blocks;Fluorinating Reagents & Building Blocks for Fluorinated Biochemical Compounds;Synthetic Organic Chemistry;Aliphatics;Esters;Organic Fluorides;Fluorochemicals;Pharmaceutical Intermediates;top;bc0001;372-31-6
Mol File:372-31-6.mol
Ethyl Trifluoroacetoacetate Structure
Ethyl Trifluoroacetoacetate Chemical Properties
Melting point -39 °C
Boiling point 129-130 °C(lit.)
density 1.259 g/mL at 25 °C(lit.)
vapor pressure 8hPa at 20℃
refractive index n20/D 1.375(lit.)
Fp 84 °F
storage temp. Sealed in dry,Room Temperature
solubility 10g/l
form Liquid
pka7.76±0.10(Predicted)
color Clear colorless to slightly yellow
Specific Gravity1.259 (20/4℃)
PH6.2 (10g/l, H2O, 20℃)
Water Solubility 10 g/L (20 ºC)
BRN 608353
InChIKeyOCJKUQIPRNZDTK-UHFFFAOYSA-N
CAS DataBase Reference372-31-6(CAS DataBase Reference)
NIST Chemistry ReferenceButanoic acid, 4,4,4-trifluoro-3-oxo-, ethyl ester(372-31-6)
EPA Substance Registry SystemEthyl 4,4,4-trifluoroacetoacetate (372-31-6)
Safety Information
Hazard Codes Xn,F,C,Xi
Risk Statements 10-22-52/53
Safety Statements 61-16
RIDADR UN 3272 3/PG 3
WGK Germany 2
Hazard Note Flammable/Corrosive
TSCA T
HazardClass 3
PackingGroup III
HS Code 29183000
MSDS Information
ProviderLanguage
Ethyl 3-oxo-4,4,4-trifluoroacetoacetate English
SigmaAldrich English
ACROS English
ALFA English
Ethyl Trifluoroacetoacetate Usage And Synthesis
Chemical PropertiesClear liquid
UsesEthyl 4,4,4-trifluoroacetoacetate is used in the synthesis of fluorinated 2-thiouracil analogs as antithyroid agents.
UsesWidely used in the synthetic process of medicine, pesticides and organic intermediate.
UsesIntermediate for agro chemicals and pharmaceuticals (mefloquine). Product Data Sheet
Flammability and ExplosibilityFlammable
SynthesisWith an ethanol solution of sodium ethoxide as a catalyst and in the presence of an organic solvent, ethyl trifluoroacetate and ethyl acetate are subjected to a Claisen condensation reaction, and ethyl 4,4,4-trifluoroacetoacetate is synthesized.
Ethyl Trifluoroacetoacetate Preparation Products And Raw materials
Raw materialsTrifluoroacetic acid
Preparation Products4-BROMO-6-(TRIFLUOROMETHYL)PYRIMIDINE-->5-(TRIFLUOROMETHYL)-1-METHYL-1H-PYRAZOLE-4-CARBONYL CHLORIDE-->(5-(TRIFLUOROMETHYL)-1-METHYL-1H-PYRAZOL-4-YL)METHANAMINE-->4-(Trifluoromethyl)-2-(methylthio)pyrimidine-5-carboxylic acid ,97%-->5-(TRIFLUOROMETHYL)-1-PHENYL-1H-PYRAZOLE-4-CARBOXAMIDE-->4-TRIFLUOROMETHYL-QUINOLINE-2-CARBOXYLIC ACID-->6-Fluoro-4-(trifluoromethyl)quinolin-2-amine ,97%-->ethyl 2-(methylsulfanyl)-4-(trifluoromethyl)pyrimidine-5-carboxylate-->4-(Trifluoromethyl)quinoline-2-carbohydrazide ,97%-->(5-(TRIFLUOROMETHYL)-1-METHYL-1H-PYRAZOL-4-YL)METHANOL-->4-(Trifluoromethyl)quinolin-2-amine-->5-(TRIFLUOROMETHYL)-1-METHYL-1H-PYRAZOLE-4-CARBOXAMIDE-->(4-(Trifluoromethyl)quinolin-2-yl)methanol ,97%-->(6-Fluoro-4-(trifluoromethyl)quinolin-2-yl)methanol ,97%-->1-PHENYL-5-(TRIFLUOROMETHYL)PYRAZOLE-4-CARBONYL CHLORIDE-->(1-TERT-BUTYL-5-(TRIFLUOROMETHYL)-1H-PYRAZOL-4-YL)METHANOL-->(5-(TRIFLUOROMETHYL)-1-PHENYL-1H-PYRAZOL-4-YL)METHANAMINE-->(5-(TRIFLUOROMETHYL)-1-PHENYL-1H-PYRAZOL-4-YL)METHANOL-->7-HYDROXY-4-(TRIFLUOROMETHYL)COUMARIN-->4-HYDROXY-2-(METHYLTHIO)-6-(TRIFLUOROMETHYL)PYRIMIDINE-->4-BROMO-6-FLUORO-2-(TRIFLUOROMETHYL)QUINOLINE-->1-PHENYL-5-(TRIFLUOROMETHYL)-1H-PYRAZOLE-4-CARBOXYLIC ACID-->ETHYL 2-PHENYL-3-(TRIFLUOROMETHYL)PYRAZOLE-4-CARBOXYLATE-->4-Methylpyrimidine-->ETHYL 1-(TERT-BUTYL)-5-(TRIFLUOROMETHYL)-1H-PYRAZOLE-4-CARBOXYLATE-->4-bromo-2-(trifluoromethyl)quinoline-->Ethyl 6-fluoro-4-(trifluoromethyl)quinoline-2-carboxylate ,97%-->4-HYDROXY-2-METHYL-6-TRIFLUOROMETHYLPYRIMIDINE-->2,6-BIS(TRIFLUOROMETHYL)-4-HYDROXYQUINOLINE-->ETHYL 3-(TRIFLUOROMETHYL)PYRAZOLE-4-CARBOXYLATE-->1-METHYL-5-(TRIFLUOROMETHYL)-1H-PYRAZOL-3-OL-->2-BROMO-4-(TRIFLUOROMETHYL)QUINOLINE-->2-Bromo-6-fluoro-4-(trifluoromethyl)quinoline-->4-HYDROXY-2-(TRIFLUOROMETHYL)QUINOLINE
Tag:Ethyl Trifluoroacetoacetate(372-31-6) Related Product Information
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