人永生化肝细胞
中文名称 | 人永生化肝细胞 |
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中文同义词 | 人永生化肝细胞;C3A (70-77),ASHLGLAR;C3A人肝母细胞癌细胞;补体C3A(人)ELISA试剂盒;人肝母细胞癌细胞 |
英文名称 | C3A (70-77) |
英文同义词 | C3A (70-77);ASHLGLAR;H-ALA-SER-HIS-LEU-GLY-LEU-ALA-ARG-OH;ALA-SER-HIS-LEU-GLY-LEU-ALA-ARG;ANAPHYLATOXIN C3A FRAGMENT 70-77;C3a;Complement C3a, (70-77);complement 3a (70-77) |
CAS号 | 63555-63-5 |
分子式 | C35H61N13O10 |
分子量 | 823.94 |
EINECS号 | |
相关类别 | 多肽;细胞系-human细胞系;细胞-细胞系;试剂盒-ELISA试剂盒;生化试剂;目录多肽;试剂盒;peptide |
Mol文件 | 63555-63-5.mol |
结构式 |
人永生化肝细胞 性质
密度 | 1.44±0.1 g/cm3(Predicted) |
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储存条件 | −20°C |
溶解度 | 溶于二甲基亚砜 |
酸度系数(pKa) | 3.34±0.10(Predicted) |
Complement system
The direct interaction of C3a(70-77) with human mononuclear leukocytes in culture results in a concentration-dependent inhibition of the generation of LIF evoked by mitogens and by the antigen SK-SD. The extent of suppression of LIF generation by C3a(70-77) is significant at concentrations of 10
-7
M or higher and exceeds 75% at 10
-6
M, irrespective of the stimulus.
C3a (70-77) induces histamine release and degranulation of rat mast cells, promotes contraction of guinea pig ileal tissue, and enhances vascular permeability in human skin. C3a (70-77) selectively desensitizes ileal smooth muscle to C3a but not to human C5a, a related anaphylatoxin. Conversely, C3a-(70-77) is unable to contract ileal smooth muscle pretreated with natural C3a. This cross-desensitization indicates a specific interaction of C3a (70-77) with cellular C3a binding sites.
安全信息
WGK Germany | 3 |
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提供商 | 语言 |
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英文
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