- 4-Biphenylacetic acid
-
- $20.00 / 1kg
-
2024-05-29
- CAS:5728-52-9
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 5000 Ton
- 4-Biphenylacetic acid
-
- $50.00 / 1KG
-
2024-05-10
- CAS:5728-52-9
- Min. Order: 1KG
- Purity: 0.99
- Supply Ability: 20 tons
- 4-Biphenylacetic acid
-
- $0.00 / 25KG
-
2023-09-08
- CAS:5728-52-9
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 50000KG/month
|
| | 4-Biphenylacetic acid Basic information |
| | 4-Biphenylacetic acid Chemical Properties |
| Melting point | 159-160 °C (lit.) | | Boiling point | 312.08°C (rough estimate) | | density | 1.1035 (rough estimate) | | refractive index | 1.6000 (estimate) | | storage temp. | 2-8°C | | solubility | DMSO: soluble50mg/mL, clear, colorless to yellow | | pka | 4.29±0.10(Predicted) | | form | Powder | | color | Beige | | Water Solubility | 39.27mg/L(25 ºC) | | Merck | 14,3316 | | BRN | 1211592 | | InChI | InChI=1S/C14H12O2/c15-14(16)10-11-6-8-13(9-7-11)12-4-2-1-3-5-12/h1-9H,10H2,(H,15,16) | | InChIKey | QRZAKQDHEVVFRX-UHFFFAOYSA-N | | SMILES | C1(C2=CC=CC=C2)=CC=C(CC(O)=O)C=C1 | | CAS DataBase Reference | 5728-52-9(CAS DataBase Reference) |
| | 4-Biphenylacetic acid Usage And Synthesis |
| Description | Felbinac Is the active metabolite of the non-steroidal antiinflammatory agent,
fenbufen. Applied topically as a gel to joints, it is useful in the symptomatic relief
of articular inflammation and pain. | | Chemical Properties | Off-white powder | | Originator | Lederle (USA) | | Uses | Anti-inflammatory, analgesic drug. | | Uses | 4-Biphenylacetic acid was used in the synthesis of gastrosparing non-steroidal antiinflammatory drug. | | Definition | ChEBI: Biphenyl-4-ylacetic acid is a monocarboxylic acid in which one of the alpha-hydrogens is substituted by a biphenyl-4-yl group. An active metabolite of fenbufen, it is used as a topical medicine to treat muscle inflammation and arthritis. It has a role as a non-steroidal anti-inflammatory drug. It is a member of biphenyls and a monocarboxylic acid. It contains a biphenyl-4-yl group. It is functionally related to an acetic acid. | | Brand name | Dolinac (Wyeth-Ayerst); Flexfree(Wyeth-Ayerst); Napageln (Wyeth-Ayerst); Target
(Wyeth-Ayerst); Traxam (Wyeth-Ayerst). | | General Description | 4-Biphenylacetic acid is a potential non-steroidal antiinflammatory agent and forms solid inclusion complex with β-cyclodextrin. 4-Biphenylacetic acid on interaction with quinolone antibacterial agents induces functional blockade of the γ-aminobutyric acid receptors. | | Safety Profile | Poison by subcutaneous route.Moderately toxic by ingestion and intraperitoneal routes.An experimental teratogen. Other experimentalreproductive effects. When heated to decomposition itemits acrid smoke and fumes. |
| | 4-Biphenylacetic acid Preparation Products And Raw materials |
|