| Company Name: |
BOC Sciences
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16314854226 |
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info@bocsci.com |
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Product Name:Diminutol
CAS:361431-33-6
Purity:98% Package:1G;10G;100G
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| Company Name: |
Shanghai Hongye Biotechnology Co. Ltd
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400-9205774 |
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sales@glpbio.cn |
| Products Intro: |
Product Name:Diminutol
CAS:361431-33-6
Purity:>98% Package:1mg;10mg;50mg;100mg;
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| Company Name: |
DC Chemicals
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021-58447131 13564518121 |
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sales@dcchemicals.com |
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Product Name:Diminutol
CAS:361431-33-6
Purity:98% HPLC Package:100mg，250mg，1g
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| Company Name: |
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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18818260767 |
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sales@chemegen.com |
| Products Intro: |
Product Name:Diminutol
CAS:361431-33-6
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
|
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| | Diminutol Basic information |
| Product Name: | Diminutol | | Synonyms: | Diminutol;1-Butanol, 2-[[6-[(3-aminophenyl)thio]-9-(1-methylethyl)-9H-purin-2-yl]amino]-3-methyl-, (2R)-;NG72 | | CAS: | 361431-33-6 | | MF: | C19H26N6OS | | MW: | 386.51 | | EINECS: | | | Product Categories: | | | Mol File: | 361431-33-6.mol |  |
| | Diminutol Chemical Properties |
| storage temp. | Store at -20°C | | solubility | DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS(pH7.2) (1:1): 0.5 mg/ml; Ethanol: 20 mg/ml | | form | A crystalline solid |
| | Diminutol Usage And Synthesis |
| Description | Diminutol is a cell-permeable purine derivative that inhibits the NADP-dependent oxidoreductase, NQO1 (Ki = 1.72 μM), to destabilize microtubules and disrupt mitosis. At 50 μM, it directly affects tubulin polymerization in Xenopus egg extracts without interfering with the activity of Cdk1, DNA replication, or actin polymerization. | | Uses | Diminutol is a cell-permeable purine analog that inhibits NQ01 and blocks mitotic spindle assembly. | | Uses | Diminutol is a cell-permeable purine derivative that inhibits the NADP-dependent oxidoreductase, NQO1 (Ki = 1.72 μM), to destabilize microtubules and disrupt mitosis. At 50 μM, it directly affects tubulin polymerization in Xenopus egg extracts without interfering with the activity of Cdk1, DNA replication, or actin polymerization.[Cayman Chemical] |
| | Diminutol Preparation Products And Raw materials |
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