Company Name: |
Amatek Scientific Co. Ltd.
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Tel: |
0512-56316828 |
Email: |
info@amateksci.com |
Products Intro: |
Product Name:HOOCCH2CH2O-PEG10-CH2CH2COOH CAS:2097010-30-3 Purity:97% HPLC Package:1g;5g;25g;100g
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Company Name: |
Xi'an Confluore Biological Technology Co., Ltd.
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Tel: |
+86-156-80926068 +86-15680926068 |
Email: |
1924344760@qq.com |
Products Intro: |
Product Name:Bis-PEG11-acid CAS:2097010-30-3 Purity:98% HPLC Package:10MG;25MG;50MG;100MG;1G;5G Remarks:For customers outside China,please use the website:www.confluore.com
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HOOCCH2CH2O-PEG10-CH2CH2COOH manufacturers
- Bis-PEG11-acid
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- $0.00 / 1g
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2024-03-24
- CAS:2097010-30-3
- Min. Order: 1g
- Purity: >98.00%
- Supply Ability: 1g
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| HOOCCH2CH2O-PEG10-CH2CH2COOH Basic information |
Product Name: | HOOCCH2CH2O-PEG10-CH2CH2COOH | Synonyms: | HOOCCH2CH2O-PEG10-CH2CH2COOH;HOOCCH2CH2-PEG10-CH2CH2COOH;4,7,10,13,16,19,22,25,28,31,34-Undecaoxaheptatriacontanedioic acid;Di-Acid-PEG11;HOOCCH2CH2O-PEG10-CH2CH2COOH/4,7,10,13,16,19,22,25,28,31,34-undecaoxaheptatriacontane-1,37-dioic acid | CAS: | 2097010-30-3 | MF: | C26H50O15 | MW: | 602.67 | EINECS: | | Product Categories: | peg | Mol File: | 2097010-30-3.mol | |
| HOOCCH2CH2O-PEG10-CH2CH2COOH Chemical Properties |
Boiling point | 684.6±55.0 °C(Predicted) | density | 1.165±0.06 g/cm3(Predicted) | pka | 3.97±0.10(Predicted) |
| HOOCCH2CH2O-PEG10-CH2CH2COOH Usage And Synthesis |
Biological Activity | Bis-PEG11-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. | References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
| HOOCCH2CH2O-PEG10-CH2CH2COOH Preparation Products And Raw materials |
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