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2-Fluoro-5-methoxy-4-nitrobenzoic acid

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CAS:1001345-80-7
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CAS:1001345-80-7
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CAS:1001345-80-7
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Products Intro: Product Name:2-fluoro-5-methoxy-4-nitro-benzoic acid
CAS:1001345-80-7
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2-Fluoro-5-methoxy-4-nitrobenzoic acid Basic information
Product Name:2-Fluoro-5-methoxy-4-nitrobenzoic acid
Synonyms:2-Fluoro-5-methoxy-4-nitrobenzoic acid;Benzoic acid, 2-fluoro-5-methoxy-4-nitro-
CAS:1001345-80-7
MF:C8H6FNO5
MW:215.14
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Mol File:1001345-80-7.mol
2-Fluoro-5-methoxy-4-nitrobenzoic acid Structure
2-Fluoro-5-methoxy-4-nitrobenzoic acid Chemical Properties
Boiling point 413.0±45.0 °C(Predicted)
density 1.514±0.06 g/cm3(Predicted)
pka2.25±0.13(Predicted)
Safety Information
MSDS Information
2-Fluoro-5-methoxy-4-nitrobenzoic acid Usage And Synthesis
Synthesis2-Fluoro-5-methoxy-4-nitrobenzoic acid can be synthesized using various methods such as the Friedel-Crafts acylation reaction, the Suzuki-Miyaura coupling reaction, and the Buchwald-Hartwig amination reaction.  The Friedel-Crafts acylation reaction involves the reaction of 2-fluoro-5-methoxy-4-nitrobenzoyl chloride with methanol in the presence of a catalyst such as aluminum chloride.  The Suzuki-Miyaura coupling reaction involves the reaction of 2-fluoro-5-methoxy-4-nitrophenylboronic acid with 4-chlorobenzoic acid in the presence of a palladium catalyst.  The Buchwald-Hartwig amination reaction involves the reaction of 2-fluoro-5-methoxy-4-nitroiodobenzene with potassium phthalimide in the presence of a palladium catalyst.
2-Fluoro-5-methoxy-4-nitrobenzoic acid Preparation Products And Raw materials
Preparation ProductsTAK-960
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