硝吡咯菌素
| 中文名称 | 硝吡咯菌素 |
|---|---|
| 中文同义词 | 吡咯尼林;氯吡咯硝苯;皮硝霉素;硝吡咯菌素;吡咯菌素;3-氯-4-(3-氯-2-硝基-苯基)-1H-吡咯 |
| 英文名称 | PYRROLNITRIN |
| 英文同义词 | 3-chloro-4-(2’-nitro-3’-chlorophenyl)pyrrole;3-chloro-4-(3-chloro-2-nitrophenyl)-pyrrol;nsc-107654;pyroace;pyrollnitrin;PYRROLE,3-CHLORO-4-(3-CHLORO-2-NITROPHENYL)-;52230;A-10338 |
| CAS号 | 1018-71-9 |
| 分子式 | C10H6Cl2N2O2 |
| 分子量 | 257.07 |
| EINECS号 | 213-812-7 |
| 相关类别 | 化工原料 |
| Mol文件 | 1018-71-9.mol |
| 结构式 |  |
硝吡咯菌素 性质
| 熔点 | 124.5° |
|---|---|
| 沸点 | 410.5±45.0 °C(Predicted) |
| 密度 | 1.5834 (rough estimate) |
| 折射率 | 1.6100 (estimate) |
| 储存条件 | Store at -20°C |
| 溶解度 | 二甲基亚砜：10mM |
| 形态 | 固体 |
| 酸度系数(pKa) | 14.28±0.50(Predicted) |
Target: fungi, yeast and gram-positive bacteria
Pyrrolnitrin (0-100 μg/ml) shows antibiotic activities against various bacteria and fungi with different MIC values. It against Staphylococcus aureus , Mycobacterium , Bacillus subtillis , Candida albicans , Aspergillus niger , and Trichophyton rubrum with MIC values of 50 μg/ml, 100 μg/ml, 0.78 μg/ml, 10 μg/ml, 12.5 μg/ml, and 1 μg/ml, respectively. Pyrrolnitrin (0-100 μg/ml) exhibits antimicrobial effect in a microtitre plate assay. It against Arthrobacter oxydans ATCC 14358, Bacillus coagulans ATCC 7050, Bacillus licheniformis ATCC 14580, Bacillus subtilis ATCC 6051, and Bacillus thuringiensis ATCC 10792 with MIC of 6.25 μg/ml.
安全信息
| 毒性 | LD50 in rats, rabbits (mg/kg): 68, 105 i.p. (Nishida) |
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