阿尼扎芬
| 中文名称 | 阿尼扎芬 |
|---|---|
| 中文同义词 | 阿尼扎芬;化合物 T14292 |
| 英文名称 | anitrazafen |
| 英文同义词 | 5,6-Bis(4-methoxyphenyl)-3-methyl-1,2,4-triazine;5,6-Bis(p-methoxyphenyl)-3-methyl-1,2,4-triazine;LY-122512;anitrazafen;1,2,4-Triazine, 5,6-bis(4-methoxyphenyl)-3-methyl- |
| CAS号 | 63119-27-7 |
| 分子式 | C18H17N3O2 |
| 分子量 | 307.35 |
| EINECS号 | |
| 相关类别 | |
| Mol文件 | 63119-27-7.mol |
| 结构式 |  |
阿尼扎芬 性质
| 沸点 | 482.8±55.0 °C(Predicted) |
|---|---|
| 密度 | 1.164±0.06 g/cm3(Predicted) |
| 储存条件 | Store at -20°C |
| 溶解度 | 溶于二甲基亚砜 |
| 酸度系数(pKa) | 1.85±0.63(Predicted) |
Anitrazafen 是一种局部有效的抗炎剂。
Anitrazafen is a topically effective antiinflammatory agent. The disposition of 14 C in normal and in bile-duct cannulated rats after oral administration of a single dose of 25 mg/kg of [3- 14 C]Anitrazafen shows the drug to be well absorbed from the gastro-intestinal tract and biliary excretion to be the major route of elimination of drug and/or metabolites. Plasma concentrations of total 14 C after subcutaneous administration of [3- 14 C]Anitrazafen in corn oil solution are about one half those found after oral administration.