| Company Name: |
Zhejiang Huida Biotech Co., LTD
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| Tel: |
0571-89903882 13626641628 |
| Email: |
jiangnan@huidabiotech.com |
| Products Intro: |
Product Name:Ascamycin
CAS:91432-48-3
Purity:99% HPLC Package:10mg；100mg；1g；10g；100g
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| | ascamycin Basic information |
| Product Name: | ascamycin | | Synonyms: | ascamycin;(+)-5'-O-[[(S)-2-Amino-1-oxopropyl]aminosulfonyl]-2-chloroadenosine;2-Chloro-5'-O-[(L-alanylamino)sulfonyl]adenosine;2-Chloro-5'-O-[[(S)-2-amino-1-oxopropyl]sulfamoyl]adenosine | | CAS: | 91432-48-3 | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | 91432-48-3.mol |  |
| | ascamycin Chemical Properties |
| | ascamycin Usage And Synthesis |
| Biological Activity | Ascamycin is a 5'-O-sulfonamide ribonucleoside antibiotic produced by Streptomyces sp. JCM9888. It has selective antibacterial activity against Xanthomonas bacteria, with MIC values of 0.4 μg/mL, 12.5 μg/mL and 12.5 μg/mL for Xanthomonas citri, Xanthomonas oryzae and Mycobacterium phlei, respectively. | | in vitro | The Ascamycin has C2-chloroadenine as the base on C-1' which lacks the chlorine. Ascamycin has a selective antibacterial activity against Xanthomonas species. When Ascamycin is dealanylated, Dealanylascamycin shows a broad antibacterial activity against various Gram-negative and Gram-positive bacteria. Xanthomonas citri is susceptible to Ascamycin by virtue of the Ascamycin-dealanylating enzyme on the cell surface. | | target | MIC: 0.4 μg/mL ( Xanthomonas citri ), 12.5 μg/mL ( Xanthomonas oryzae ) and 12.5 μg/mL ( Mycobacterium phlei ) |
| | ascamycin Preparation Products And Raw materials |
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