- 6-Aminofluorescein
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- $1.00 / 1KG
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2024-04-24
- CAS:51649-83-3
- Min. Order: 1KG
- Purity: 99.91%
- Supply Ability: 200000
- 6-Aminofluorescein
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- $0.00 / 25KG
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2023-09-06
- CAS:51649-83-3
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 500000kg
- 6-Aminofluorescein
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- $0.00 / 25KG
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2023-06-30
- CAS:51649-83-3
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 50000KG/month
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| | 6-Aminofluorescein Basic information |
| | 6-Aminofluorescein Chemical Properties |
| Melting point | 285 °C (dec.)(lit.) | | Boiling point | 481.89°C (rough estimate) | | density | 1.3724 (rough estimate) | | refractive index | 1.5180 (estimate) | | storage temp. | 2-8°C | | solubility | methanol: soluble1mg/mL, clear, yellow to very dark yellow-orange | | pka | 9.34±0.20(Predicted) | | form | Solid | | color | Yellow to Orange | | BRN | 51708 | | Stability: | Light and Moisture Sensitive | | InChI | InChI=1S/C20H13NO5/c21-10-1-4-13-16(7-10)20(26-19(13)24)14-5-2-11(22)8-17(14)25-18-9-12(23)3-6-15(18)20/h1-9,22-23H,21H2 | | InChIKey | YOAWSYSKQHLFPM-UHFFFAOYSA-N | | SMILES | C12(C3=C(C=C(O)C=C3)OC3=C1C=CC(O)=C3)C1=C(C=CC(N)=C1)C(=O)O2 | | CAS DataBase Reference | 51649-83-3(CAS DataBase Reference) |
| | 6-Aminofluorescein Usage And Synthesis |
| Description | 6-Aminofluorescein (6-AF) is a new fluorescence dye with bright colors and high fluorescence intensity. Its chemical structure history contains a nitrogen group and a fluorescent group. The presence of the fluorescent component enables 6-Aminofluorescein to emit a distinct fluorescent signal when excited, making it valuable for fluorescent labeling and imaging. It is widely used in biological science research, chemical analysis and fluorescence microscopy. | | Chemical Properties | Yellow Solid | | Uses | Fluorescent labeling reagent for proteins. Glycosaminoglycuronans react with 6-aminofluorescein to yield fluorescent derivatives. Used in the fluorescent antibody technique for rapid identification of pathogens. | | Biological Functions | 6-Aminofluorescein has been demonstrated to be useful fluorescent labeling reagent for fullerene-based liposome nanostructures termed "buckysomes". 6-aminofluorescein dissolved in 0.1 N NaOH can be quantified from a maximum absorbance at 490 nm. Decarboxylated 6-aminofluorescein dissolved 6 N HCl (prepare by constant boiling at 110° C for 24 h) can be quantified from a maximum absorbance at 454 nm. Aldehyde groups are formed by oxidateive damage to proteins, which can be detected by conjugation to decarboxylated 6-aminofluorescein. 6-Aminofluorescein has been used to determine its ability to potentiate the antiviral activity of poly r (A-U). | | References | [1] BHARATE G Y, QIN H, FANG J. Poly(Styrene-Co-Maleic Acid)-Conjugated 6-Aminofluorescein and Rhodamine Micelle as Macromolecular Fluorescent Probes for Micro-Tumors Detection and Imaging[J]. Journal of Personalized Medicine, 2022, 12. DOI:10.3390/jpm12101650.
[2] Müller, Werner EG, and Heinz Christoph Schr?der, eds. Biological Response Modifiers—Interferons, Double-Stranded RNA and 2′, 5′-Oligoadenylates. Vol. 14. Springer Science & Business Media, 2012. |
| | 6-Aminofluorescein Preparation Products And Raw materials |
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