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| | PROPOXYPHENE HYDROCHLORIDE Basic information |
| Product Name: | PROPOXYPHENE HYDROCHLORIDE | | Synonyms: | DARVON;DEXTROPROPOXYPHENE HYDROCHLORIDE;Propoxyphene Hydrochloride CII (1 g);PROPOXYPHENE HYDROCHLORIDE;(+)-1,2-diphenyl-2-propionoxy-3-methyl-4-dimethylaminobutanehydrochloride;D-PROPOXYPHENE HCL NARCOTIC ANALGESIC;(aS)-a-[(1R)-2-(Dimethylamino)-1-methylethyl]-a-phenylbenzeneethanol Propanoate Hydrochloride;a-d-Propoxyphene Hydrochloride | | CAS: | 1639-60-7 | | MF: | C22H29NO2.ClH | | MW: | 375.93 | | EINECS: | 216-683-5 | | Product Categories: | Intermediates & Fine Chemicals;Pharmaceuticals;Amines;Aromatics | | Mol File: | 1639-60-7.mol |  |
| | PROPOXYPHENE HYDROCHLORIDE Chemical Properties |
| Hazard Codes | F,T | | Risk Statements | 11-23/24/25-39/23/24/25 | | Safety Statements | 16-36/37-45 | | RIDADR | 3249 | | HazardClass | 6.1(b) | | PackingGroup | III | | Toxicity | LD50 in mice, rats (mg/kg): 28, 15 i.v.; 111, 58 i.p.; 211, 134 s.c.; 282, 230 orally (Emerson) |
| | PROPOXYPHENE HYDROCHLORIDE Usage And Synthesis |
| Chemical Properties | White Solid | | Uses | Dextropropoxyphene is a controlled substance (narcotic) | | Uses | Dextropropoxyphene is a controlled substance (opiate). Analgesic (narcotic). The α-dl-and d-diastereoisomers possess marked analgesic activity in contrast to the β-diastereoisomers which are substantially inactive. | | Brand name | Darvon (Xanodyne); Dolene (Clonmel). | | Safety Profile | A human poison by
ingestion. An experimental poison by
ingestion, intraperitoneal, subcutaneous,
intravenous, and intramuscular routes.
Human systemic effects by ingestion:
anorexia, ataxia, chronic pulmonary edema,
cyanosis, increased body temperature,
jaundice, nausea or vomiting, sleep
disturbance. Experimental teratogenic and
reproductive effects. When heated to
decomposition it emits very toxic fumes of
HCl and NOx. See also
PROPOXYPHENE. |
| | PROPOXYPHENE HYDROCHLORIDE Preparation Products And Raw materials |
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