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| | 3-(2-FURANYLMETHYL)-3,7-DIHYDRO-1,8-DIMETHYL-1H-PURINE-2,6-DIONE Basic information |
| Product Name: | 3-(2-FURANYLMETHYL)-3,7-DIHYDRO-1,8-DIMETHYL-1H-PURINE-2,6-DIONE | | Synonyms: | FURAFYLLINE;3-(2-FURANYLMETHYL)-3,7-DIHYDRO-1,8-DIMETHYL-1H-PURINE-2,6-DIONE;Furafylline,3-(2-Furanylmethyl)-3,7-dihydro-1,8-dimethyl-1H-purine-2,6-dione;FURAFYLLINE INHIBITOR OF CYTOCHRO;1H-Purine-2,6-dione, 3-(2-furanylmethyl)-3,9-dihydro-1,8-dimethyl-;3-(Furan-2-ylmethyl)-1,8-dimethyl-1H-purine-2,6(3H,7H)-dione;Cytochrome P450,inhibit,Inhibitor,CYPs,Furafylline;Furatheophylline | | CAS: | 80288-49-9 | | MF: | C12H12N4O3 | | MW: | 260.25 | | EINECS: | 200-158-5 | | Product Categories: | | | Mol File: | 80288-49-9.mol |  |
| | 3-(2-FURANYLMETHYL)-3,7-DIHYDRO-1,8-DIMETHYL-1H-PURINE-2,6-DIONE Chemical Properties |
| Melting point | >162°C (dec.) | | Boiling point | 543.6±60.0 °C(Predicted) | | density | 1.443±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C(protect from light) | | solubility | ethanol: 0.33 mg/mL | | form | solid | | pka | 8.62±0.70(Predicted) | | color | white | | InChIKey | KGQZGCIVHYLPBH-UHFFFAOYSA-N |
| | 3-(2-FURANYLMETHYL)-3,7-DIHYDRO-1,8-DIMETHYL-1H-PURINE-2,6-DIONE Usage And Synthesis |
| Uses | Furafylline is a selective inhibitor of human cytochrome P450. It is also reported to inhibit the oxidation of caffeine. | | Definition | ChEBI: Furafylline is an oxopurine. | | Biochem/physiol Actions | Furafylline (1,8-dimethyl-3-(2′ -furfuryl)methylxanthine) is a xanthine derivative. It is preferred in treating asthma. It serves as a N3-demethylation inhibitor of caffeine. Furafylline does not show much effect on human monooxygenase activities. It is considered as an efficient bronchodilator and as an inhibitor of anaphylactic reactions, when compared to theophylline. |
| | 3-(2-FURANYLMETHYL)-3,7-DIHYDRO-1,8-DIMETHYL-1H-PURINE-2,6-DIONE Preparation Products And Raw materials |
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