| Company Name: |
J & K SCIENTIFIC LTD.
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| Tel: |
010-82848833 400-666-7788 |
| Email: |
jkinfo@jkchemical.com |
| Products Intro: |
Product Name:Phenamil.Methanesulfonate
CAS:2038-35-9
Purity:>97% Package:5mg, 25mg
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| Company Name: |
3B Pharmachem (Wuhan) International Co.,Ltd.
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| Tel: |
821-50328103-801 18930552037 |
| Email: |
3bsc@sina.com |
| Products Intro: |
Product Name:PHENAMIL
CAS:2038-35-9
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
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| Company Name: |
Jinan Yaoyan Pharmaceutical Co., Ltd.
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| Tel: |
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| Email: |
jnyaoyan@163.com |
| Products Intro: |
Product Name:Phenamil methanesulfonate (free base)
CAS:2038-35-9
Purity:99% HPLC Package:1, 2, 5 gr
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| | PHENAMIL Basic information |
| Product Name: | PHENAMIL | | Synonyms: | PHENAMIL;3,5-DIAMINO-6-CHLORO-N-[IMINO(PHENYLAMINO)METHYL]-PYRAZINECAR-BOXAMIDE;3,5-diamino-6-chloro-n-[imino(phenylamino)methyl]pyrazinecarboxamide methanesulfonate salt;phenamil methanesulfonate salt;phenylamil;3,5-Diamino-6-chloro-N-[imino(phenylamino)methyl]pyrazine-2-carboxamide;3,5-bis(azanyl)-N-[azanyl-(phenylamino)methylidene]-6-chloro-pyrazine-2-carboxamide;3,5-diamino-N-[amino(anilino)methylene]-6-chloro-pyrazinamide | | CAS: | 2038-35-9 | | MF: | C12H12ClN7O | | MW: | 305.72 | | EINECS: | | | Product Categories: | | | Mol File: | 2038-35-9.mol |  |
| | PHENAMIL Chemical Properties |
| Melting point | >181°C (dec.) | | density | 1.65±0.1 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | DMSO: >15 mg/mL | | form | solid | | pka | 8.10±0.46(Predicted) | | color | yellow |
| | PHENAMIL Usage And Synthesis |
| Uses | Phenamil Methanesulfonate Salt induced differentiation and peroxisome proliferator-activator receptor γ expression through ETS variant 4 in mouse preadipocyte | | Definition | ChEBI: Phenylamil is a member of pyrazines and a member of guanidines. | | Enzyme inhibitor | This amiloride derivative (FW = 306.73 g/mol; CAS 2038-35-9), also known as 3,5-diamino-6-chloro-N-[imino(phenylamino)methyl]pyrazine carboxamide, irreversibly inhibits amiloride-sensitive Na+ channels. It is often supplied commercially as the methanesulfonate salt. Na+ channel blockers, such as phenamil and benzamil, are be alsoing explored as a way to counteract the hyperabsorption of NaCl in cystic fibrosis airways. Target(s): diamine oxidase; Na+ channels; and Na+ -driven flagellar motility. |
| | PHENAMIL Preparation Products And Raw materials |
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