6-全脱氧-6-全溴代-Γ-环糊精
| 中文名称 | 6-全脱氧-6-全溴代-Γ-环糊精 |
|---|---|
| 中文同义词 | 八-(6-溴-6-脱氧)-伽马-环糊精;八-(6-溴-6-脱氧)-GAMMA-环糊精;八-(6-溴-6-脱氧)-GAMMA-环糊精 舒更葡糖钠中间体;6-全脱氧-6-全溴代-Γ-环糊精;舒更葡糖钠杂质38;舒更葡糖杂质3;八(6-溴-6-去氧)伽马环糊精;八(6-溴-6-去氧)-Γ-环糊精 |
| 英文名称 | OCTAKIS-6-BROMO-6-DEOXY-GAMMA-CYCLODEXTRIN |
| 英文同义词 | 6-Bromo-6-deoxy-gamma-cyclodextrin;Octakis(6-bromo-6-dexoy)-gamma-cyclodextrin;octakis(6-bromo-6-deoxy)-γ-cyclodextrin;Octakis(6-deoxy-6-bromo)-gamma-cyclodextrin;Sugammadex sodium Impurity 38;γ-Cyclodextrin,6A,6B,6C,6D,6E,6F,6G,6H-octabromo-6A,6B,6C,6D,6E,6F,6G,6H-octadeoxy;Sugammadex Impurity 1;Sugammadex Impurity 77 |
| CAS号 | 53784-84-2 |
| 分子式 | C48H72Br8O32 |
| 分子量 | 1800.3 |
| EINECS号 | 611-044-0 |
| 相关类别 | 原料药中间体 舒更葡糖钠中间体;杂质对照品;对照品-杂质对照品;有机化工;医药研发中间体 |
| Mol文件 | 53784-84-2.mol |
| 结构式 |  |
6-全脱氧-6-全溴代-Γ-环糊精 性质
| 熔点 | 213-217°C |
|---|---|
| 密度 | 1.948±0.06 g/cm3(Predicted) |
| 蒸气压 | 0.002-0.007Pa at 20-25℃ |
| 溶解度 | Soluble in DMF, DMSO. Insoluble in water, methanol, chloroform. |
| 酸度系数(pKa) | 11.56±0.70(Predicted) |
| 形态 | 固体粉末 |
| 颜色 | 米白色 |
| LogP | 3.5 at 20℃ |
Octakis-(6-bromo-6-deoxy)-γ-cyclodextrin 是一种在伯侧全溴化的γ-环糊精，也是一种环糊精改性中常用的中间体。
Octakis-(6-bromo-6-deoxy)-γ-cyclodextrin is stacked head-to-head along the a-axis forming columns. Octakis-(6-bromo-6-deoxy)-γ-cyclodextrin has a feature that alternates hydrophobic and hydrophilic layers are formed in the crystal.
安全信息
| 海关编码 | 9999999999 |
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