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Apicore Pharmaceuticals Pvt Ltd
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Product Name:Colestipol hydrochloride
CAS:37296-80-3
Purity:98% Package:1 kg,5 kg, 10 kg,25kg and 1 MT
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Rivashaa Agrotech Biopharma Pvt. Ltd.
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| Products Intro: |
Product Name:Colestipol hydrochloride
CAS:37296-80-3
Purity:98% Package:1 kg,5 kg, 10 kg,25kg
|
| Company Name: |
Apothecon Pharmaceuticals Pvt Ltd
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+91-2662244212 +91-9099007601 |
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sales@apotheconpharma.com |
| Products Intro: |
Product Name:Colestipol hydrochloride
CAS:37296-80-3
Purity:99% Package:1 kg,5 kg, 10 kg,25kg and 1 MT
|
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| | Colestipol hydrochloride Basic information |
| Product Name: | Colestipol hydrochloride | | Synonyms: | Colestipol Hydrochloride (200 mg);COLESTIPOL HCL;COLESTIPOL HYDROCHLORIDE;N-(2-AMINOETHYL)-N'-[2-[(2-AMINOETHYL)AMINO]ETHYL]-1,2-ETHANEDIAMINE POLYMER WITH (CHLOROMETHYL)OXIRANE HYDROCHLORIDE;n'-(2-aminoethyl)-n-[2-(2-aminoethylamino)ethyl]ethane-1,2-diamine 2-(chloromethyl)oxirane hydrochloride;cholestabyl;colestid;lestid | | CAS: | 37296-80-3 | | MF: | C8H24ClN5 | | MW: | 225.76266 | | EINECS: | | | Product Categories: | | | Mol File: | 37296-80-3.mol |  |
| | Colestipol hydrochloride Chemical Properties |
| storage temp. | Room Temperature, under inert atmosphere | | form | Solid | | color | Off-White to Pale Yellow |
| WGK Germany | 3 | | HS Code | 3914006000 | | Toxicity | LD50 in rats (mg/kg): >4000 i.p.; >1000 orally (Webster, Bollert) |
| | Colestipol hydrochloride Usage And Synthesis |
| Uses | Antihyperlipidemic. | | Uses | Colestipol Hydrochloride was useful for studying pharmacokinetics with Teriflunomide (A771726). | | Definition | ChEBI: The hydrochloride of colestipol, a highly cross-linked, high molecular weight copolymer of diethylenetriamine and epichlorohydrin (hydrochloride), with approximately 1 out of 5 amine nitrogens protonated. It is used for binding bile acids in the intestine,
inhibiting their reabsorption. | | Brand name | Colestid (Pharmacia & Upjohn). | | General Description | Colestipol (Colestid) is ahigh–molecular-weight, insoluble, granular copolymer oftetraethylenepentamine and epichlorohydrin. It functions asan anion-exchange, resin-sequestering agent in a manner similarto that of cholestyramine resin. Colestipol hydrochloridereduces cholesterol levels without affecting triglycerides andseems to be especially effective in the treatment of type IIhyperlipoproteinemias. | | Drug interactions | Potentially hazardous interactions with other drugs
Anticoagulants: may enhance or reduce effects of
coumarins and phenindione.
Ciclosporin: no reports of an interaction; however,
ciclosporin levels should be carefully monitored if
colestipol and ciclosporin are prescribed concurrently,
as colestipol may interfere with ciclosporin
absorption. | | Metabolism | Not applicable as colestipol is not systemically absorbed. |
| | Colestipol hydrochloride Preparation Products And Raw materials |
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