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barbexaclone

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barbexaclone Basic information
Product Name:barbexaclone
Synonyms:Barbexaclon;Barbexaclonum;Maliasin;l-Form ethylphenylbarbiturate;barbexaclone;MJCBWPMBFCUHBP-UHFFFAOYSA-N
CAS:4388-82-3
MF:C12H12N2O3.C10H21N
MW:387.521
EINECS:224-504-7
Product Categories:
Mol File:4388-82-3.mol
barbexaclone Structure
barbexaclone Chemical Properties
Safety Information
MSDS Information
barbexaclone Usage And Synthesis
OriginatorMaliasin,Knoll,Italy,1983
Manufacturing Process25.4 g of sodium salt of phenyl ethyl barbituric acid and 19.1 g of 1- cyclohexyl-2-methylamino propane hydrochloride are boiled under reflux in a mixture of 125 cc of acetic acid ethyl ester and 125 cc of ethanol. After boiling for half an hour, the solution is filtered, while still hot, to separate the precipitated sodium chloride. The filtrate is concentrated by evaporation to about half its volume. After cooling 42.5 g of the salt of 1-cyclohexyl-2- methylamino propane and of phenyl ethyl barbituric acid are obtained in crystalline form. Its melting point is 130°-133°C.
Brand nameMaliasin (Knoll).
Therapeutic FunctionAntiepileptic
barbexaclone Preparation Products And Raw materials
Raw materialsPhenobarbital
Tag:barbexaclone(4388-82-3) Related Product Information
2-ETHYL-2-PHENYLMALONAMIDE HYDRATE 5-methyl-5-phenylbarbituric acid Phenobarbital 2-Ethyl-2-phenylmalonamide barbexaclone Primidone