| Company Name: |
3B Pharmachem (Wuhan) International Co.,Ltd.
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| Tel: |
821-50328103-801 18930552037 |
| Email: |
3bsc@sina.com |
| Products Intro: |
Product Name:CGP 78608 hydrochloride;[(1S)-1-[[(7-BroMo-1,2,3,4-tetrahydro-2,3-dioxo-5-quinoxalinyl)Methyl]aMino]ethyl]phosphonicacidhydrochloride
CAS:206648-13-7
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
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| Company Name: |
EMMX Biotechnology LLC
|
| Tel: |
888-539-0666 |
| Email: |
info@emmx.com |
| Products Intro: |
Product Name:CGP 78608 hydrochloride
CAS:206648-13-7
Purity:98% HPLC Package:5mg;10mg;25mg;50mg;100mg;250mg;500mg;1g
|
| Company Name: |
MedBioPharmaceutical Technology Inc
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| Tel: |
021-69568360 18916172912 |
| Email: |
order@med-bio.cn |
| Products Intro: |
Product Name:CGP 78608 HYDROCHLORIDE
CAS:206648-13-7
Purity:98% Package:50mg; 10mg Remarks:Medbio
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| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Email: |
marketing@energy-chemical.com |
| Products Intro: |
Product Name:CGP78608hydrochloride
CAS:206648-13-7
Purity:NULL Package:10mg;25mg Remarks:NULL
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| | CGP 78608 HYDROCHLORIDE Basic information |
| Product Name: | CGP 78608 HYDROCHLORIDE | | Synonyms: | [(1S)-1-[[(7-BROMO-1,2,3,4-TETRAHYDRO-2,3-DIOXO-5-QUINOXALINYL)METHYL]AMINO]ETHYL]PHOSPHONIC ACID HYDROCHLORIDE;CGP 78608 HYDROCHLORIDE;((1S)-1-(((7-Bromo-1,2,3,4-tetrahydro-2,3-dioxo-5-quinoxalinyl)methyl)amino)ethyl]phosphonicacidhydrochloride;CGP78608HCl;Phosphonic acid, P-[(1S)-1-[[(7-bromo-1,2,3,4-tetrahydro-2,3-dioxo-5-quinoxalinyl)methyl]amino]ethyl]-;CGP 78608 hydrochlor | | CAS: | 206648-13-7 | | MF: | C11H13BrN3O5P | | MW: | 378.12 | | EINECS: | | | Product Categories: | | | Mol File: | 206648-13-7.mol |  |
| | CGP 78608 HYDROCHLORIDE Chemical Properties |
| density | 1.757±0.06 g/cm3(Predicted) | | storage temp. | Store at RT | | solubility | <41.46mg/ml in 2.2eq. NaOH | | pka | 0.66±0.10(Predicted) |
| | CGP 78608 HYDROCHLORIDE Usage And Synthesis |
| Uses | CGP 78608 is a potent and selective NMDA antagonist. | | Definition | ChEBI: CGP 78608 is a phosphonic acid in which the hydrogen attached to phosphorous is substituted by a 1-{[(7-bromo-2,3-dioxo-1,2,3,4-tetrahydroquinoxalin-5-yl)methyl]amino}ethyl group. Potent and selective NMDA antagonist that acts through the glycine site (IC50 = 5 nM). Displays >500-fold selectivity over kainate and AMPA receptors (IC50 values are 2.7 and 3 muM respectively). Anticonvulsant in vivo following systemic administration. It has a role as a NMDA receptor antagonist and an anticonvulsant. It is a quinoxaline derivative, an organobromine compound, a secondary amino compound and a member of phosphonic acids. It contains a CGP 78608(1+). | | Biological Activity | Potent and selective NMDA antagonist that acts through the glycine site (IC 50 = 5 nM). Displays > 500-fold selectivity over kainate and AMPA receptors (IC 50 values are 2.7 and 3 μ M respectively). Anticonvulsant in vivo following systemic administration. Also available as part of the NMDA Receptor - Glycine Site Tocriset™ . |
| | CGP 78608 HYDROCHLORIDE Preparation Products And Raw materials |
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