GRGDSP
| 中文名称 | GRGDSP |
|---|---|
| 中文同义词 | 合成线性RGD肽;甘氨酰-精氨酰-甘氨酰-天冬氨酰-丝氨酰-脯氨酸;抑制剂多肽GRGDSP |
| 英文名称 | glycyl-arginyl-glycyl-aspartyl-seryl-proline |
| 英文同义词 | glycyl-arginyl-glycyl-aspartyl-seryl-proline;Glycyl-L-arginylglycyl-L-α-aspartyl-L-seryl-L-proline;L-Proline, glycyl-L-arginylglycyl-L-α-aspartyl-L-seryl-;Glycyl-L-arginylglycyl-L-α-aspartyl-L-seryl-L-proline |
| CAS号 | 91037-75-1 |
| 分子式 | C22H37N9O10 |
| 分子量 | 587.58 |
| EINECS号 | |
| 相关类别 | 标准品;目录多肽 |
| Mol文件 | 91037-75-1.mol |
| 结构式 |  |
GRGDSP 性质
| 储存条件 | Store at -20°C |
|---|---|
| 溶解度 | 溶于二甲基亚砜 |
| 形态 | 固体 |
GRGDSP可用于修饰心血管植入物表面，如血管移植物，促进内皮化。
GRGDSP 是一种合成的线性RGD肽，是一种整联蛋白 (integrin) 抑制剂。Integrin
It is demonstrated that transarterial infusion of GRGDSP (Gly-Arg-Gly-Asp-Ser-Pro integrin-inhibitor which includes RGD-peptide). As a synthetic linear RGD peptide, GRGDSP (Gly-Arg-Gly-Asp-Ser-Pro) can inhibit the adherence of tumor cells to endothelial cells of blood vessels and limit its metastasis. GRGDSP (Gly-Arg-Gly-Asp-Ser-Pro) is used as a soluble integrin-blocking RGD-based peptide. GRGDSP is used widely together with other RGD peptides in integrin research. GRGDSP can be used to modify the surface of cardiovascular implants such as vascular grafts to promote endothelialization.