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| | 4-((6,7-Dimethoxyquinolin-4-yl)oxy)aniline Basic information |
| Product Name: | 4-((6,7-Dimethoxyquinolin-4-yl)oxy)aniline | | Synonyms: | BenzenaMine, 4-[(6,7-diMethoxy-4-quinolinyl)oxy]-;[4-[(6,7-Dimethoxyquinolin-4-yl)oxy]phenyl]amine;4-[(6,7-Dimethoxyquinolin-4-yl)oxy]aniline;6,7-Dimethoxy-4-(4-aminophenoxy)quinoline;BenzeMine, 4-[(6,7-diMethoxy-4-quinolinyl)oxy]-;4-[(6,7-diMethoxy-4-quinolinyl)oxy]-BenzenaMine;4-(2,3-dimethoxynaphthalen-5-yloxy)benzenamine;Intermediate 1 of Cabozantinib | | CAS: | 190728-25-7 | | MF: | C17H16N2O3 | | MW: | 296.32 | | EINECS: | | | Product Categories: | | | Mol File: | 190728-25-7.mol |  |
| | 4-((6,7-Dimethoxyquinolin-4-yl)oxy)aniline Chemical Properties |
| Melting point | 211.0 to 215.0 °C | | Boiling point | 481.8±45.0 °C(Predicted) | | density | 1.246±0.06 g/cm3 (20 ºC 760 Torr) | | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | solubility | DMSO (Slightly, Sonicated), Methanol (Slightly) | | form | powder to crystal | | pka | 6.79±0.30(Predicted) | | color | Light yellow to Brown | | InChI | InChI=1S/C17H16N2O3/c1-20-16-9-13-14(10-17(16)21-2)19-8-7-15(13)22-12-5-3-11(18)4-6-12/h3-10H,18H2,1-2H3 | | InChIKey | VXEQRXJATQUJSN-UHFFFAOYSA-N | | SMILES | C1(N)=CC=C(OC2C3C(N=CC=2)=CC(OC)=C(OC)C=3)C=C1 |
| | 4-((6,7-Dimethoxyquinolin-4-yl)oxy)aniline Usage And Synthesis |
| Uses | 4-(6,7-Dimethoxy-Quinolin-4-Yloxy)-Phenylamine is used in preparation of Cabozantinib Defluorination impurity. | | Chemical Reactivity | 4-((6,7-Dimethoxyquinolin-4-yl)oxy)aniline is a primary alcohol that has been shown to catalyze the reaction of potassium carbonate with an alkali metal hydroxide to produce potassium. It has also been shown to be a base catalyst for the reaction of cyclopropanecarboxylic acid with an alcohol ester to produce high yield. |
| | 4-((6,7-Dimethoxyquinolin-4-yl)oxy)aniline Preparation Products And Raw materials |
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