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| 3-[BENZYL-(2-METHOXYCARBONYL-ETHYL)-AMINO]-PROPIONIC ACID METHYL ESTER Basic information | Synthesis |
Product Name: | 3-[BENZYL-(2-METHOXYCARBONYL-ETHYL)-AMINO]-PROPIONIC ACID METHYL ESTER | Synonyms: | 3-[BENZYL-(2-METHOXYCARBONYL-ETHYL)-AMINO]-PROPIONIC ACID METHYL ESTER;methyl N-benzyl-N-(3-methoxy-3-oxopropyl)-beta-alaninate;N,N-BIS(B-(METHOXYCARBONYL)ETHYL)BENZYLAMINE;3,3'-(Benzylimino)bis(propionic acid methyl) ester;3,3'-(Benzylimino)bispropionic acid dimethyl ester;3,3'-(Benzylimino)dipropionic acid dimethyl ester;3,3'-Benzyliminobis(propanoic acid methyl) ester;N-(3-Methoxy-3-oxopropyl)-N-phenylmethyl-β-alanine methyl ester | CAS: | 793-19-1 | MF: | C15H21NO4 | MW: | 279.34 | EINECS: | 212-343-5 | Product Categories: | | Mol File: | 793-19-1.mol | |
| 3-[BENZYL-(2-METHOXYCARBONYL-ETHYL)-AMINO]-PROPIONIC ACID METHYL ESTER Chemical Properties |
Boiling point | 150-161 °C(Press: 0.6 Torr) | density | 1.108±0.06 g/cm3(Predicted) | storage temp. | Sealed in dry,Room Temperature | solubility | Chloroform (Slightly), Methanol (Slightly) | form | Oil | pka | 5.79±0.50(Predicted) | color | Colourless to Pale Yellow |
| 3-[BENZYL-(2-METHOXYCARBONYL-ETHYL)-AMINO]-PROPIONIC ACID METHYL ESTER Usage And Synthesis |
Synthesis | A neat mixture of methyl acrylate 129 (63 ml, 0.70 mol) and
BnNH2 130 (25 g, 0.23 mol) was refluxed in the presence of Et3N
(65 ml, 0.46 mol) overnight. Excess methyl acrylate was distilled
off, the residue was taken in EtOAc and washed with water, brine,
dried over anhydrous Na2SO4 and filtered. Solvent removed under reduced pressure. The
resultant oil was chromatographed over silica gel using EtOAc-pet ether to furnish Michael
adduct 131 as a yellow oil (58.67 g).
| Uses | 3-[Benzyl-(2-methoxycarbonylethyl)amino]propionic Acid Methyl Ester is used in preparation of substituted Phenyloxazolidinones as antimicrobial agents for treating antimicrobial. |
| 3-[BENZYL-(2-METHOXYCARBONYL-ETHYL)-AMINO]-PROPIONIC ACID METHYL ESTER Preparation Products And Raw materials |
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