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ChemicalBook > Product Catalog >Biochemical Engineering >Inhibitors >Metabolism >PDE inhibitors >S- (+)-Rolipram

S- (+)-Rolipram

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S- (+)-Rolipram Suppliers list
Company Name: Hubei xin bonus chemical co. LTD
Tel: 86-13657291602
Email: linda@hubeijusheng.com
Products Intro: Product Name:S- (+)-Rolipram
CAS:85416-73-5
Company Name: career henan chemical co
Tel: +86-0371-86658258 15093356674;
Email: factory@coreychem.com
Products Intro: Product Name:S- (+)-Rolipram
CAS:85416-73-5
Purity:97%-99.9% Package:1KG;1USD
Company Name: Shaanxi Dideu Medichem Co. Ltd
Tel: +86-29-87569265 +86-18612256290
Email: 1056@dideu.com
Products Intro: Product Name:S- (+)-Rolipram
CAS:85416-73-5
Purity:99% HPLC Package:5mg;USD|1g;USD|500g;USD|25KG;USD|200KG;USD
Company Name: Guangzhou Yuheng Pharmaceutical Technology Co., Ltd
Tel: +8613580539051
Email: joe@yuhengpharm.com
Products Intro: Product Name:(4S)-4-[3-(cyclopentyloxy)-4-methoxyphenyl]pyrrolidin-2-one
CAS:85416-73-5
Purity:0.97 Package:1KG;25KG
Company Name: Dideu Industries Group Limited
Tel: +86-29-89586680 +86-15129568250
Email: 1026@dideu.com
Products Intro: Product Name:S- (+)-Rolipram
CAS:85416-73-5
Purity:99.9% Package:25kgs/Drum;200kgs/Drum Remarks:FDA GMP CEP Approved Manufacturer

S- (+)-Rolipram manufacturers

  • S- (+)-Rolipram
  • S- (+)-Rolipram pictures
  • $0.00 / 5mg
  • 2021-07-20
  • CAS:85416-73-5
  • Min. Order: 5mg
  • Purity: 99% HPLC
  • Supply Ability: 2000tons
  • S- (+)-Rolipram
  • S- (+)-Rolipram pictures
  • $1.00 / 1KG
  • 2020-03-16
  • CAS:85416-73-5
  • Min. Order: 1KG
  • Purity: 97%-99.9%
  • Supply Ability: 100KG
S- (+)-Rolipram Basic information
Product Name:S- (+)-Rolipram
Synonyms:(S)-(+)-ROLIPRAM;(4S)-4-(3-(Cyclopentyloxy)-4-methoxyphenyl)pyrrolidine-2-one;Rolipram (S)-(+)-;(4S)-(3-(Cyclopentyloxy)-4-methoxyphenyl)pyrrolidin-2-one;(4S)-4-[3-(CYCLOPENTYLOXY)-4-METHOXYPHENYL]PYRROLIDIN-2-ONE;(4S)-4-[3-(cyclopentoxy)-4-methoxy-phenyl]-2-pyrrolidone;(S)-4-[3-(Cyclopentyloxy)-4-methoxyphenyl]-2-pyrrolidinone;(4S)-4-[3-(cyclopentyloxy)-4-methoxyphenyl]-2-pyrrolidinone
CAS:85416-73-5
MF:C16H21NO3
MW:275.34
EINECS:
Product Categories:Signalling;Cyclic Nucleotide related;Inhibitors
Mol File:85416-73-5.mol
S- (+)-Rolipram Structure
S- (+)-Rolipram Chemical Properties
Melting point 133-136℃
density 1.155
storage temp. Sealed in dry,Store in freezer, under -20°C
solubility DMSO : 100 mg/mL (363.19 mM; Need ultrasonic)
form White to off-white solid.
color White to Almost white
Safety Information
HS Code 2933.79.1500
MSDS Information
S- (+)-Rolipram Usage And Synthesis
UsesS-(+)-Rolipram is an inhibitor of cyclic AMP-specific phosphodiesterase. It is the S isomer of (±)-Rolipram (R640040). Potent PDE4 inhibitor
UsesS-(+)-Rolipram inhibits human monocyte cyclic AMP-specific PDE4 with IC50 of 0.75 μM, has anti-inflammatory and anti-depressant activity in the central nervous system, less potent than its R enantiomer
DefinitionChEBI: The (S)-enantiomer of rolipram.
Biological ActivityLess active enantiomer of the PDE4 inhibitor rolipram (4-(3-(Cyclopentyloxy)-4-methoxyphenyl)pyrrolidin-2-one ).
storageRoom temperature
S- (+)-Rolipram Preparation Products And Raw materials
Raw materials3-CYCLOPENTYLOXY-4-METHOXYBENZALDEHYDE-->Bromocyclopentane-->Isovanillin
Preparation Products(4S)-4-[3-(CYCLOPENTYLOXY)-4-METHOXYPHENYL]PYRROLIDIN-2-ONE
Tag:S- (+)-Rolipram(85416-73-5) Related Product Information
ZARDAVERINE RO 20-1724 Roflumilast 4-(3-(CYCLOPENTYLOXY)-4-METHOXYPHENYL)PYRROLIDIN-2-ONE ETAZOLATE BRL 50481 Vinpocetine ZAPRINAST Cilostazol CILOSTAMIDE AG 1295 (4S)-4-[3-(CYCLOPENTYLOXY)-4-METHOXYPHENYL]PYRROLIDIN-2-ONE 4-[[3,4-(METHYLENEDIOXY)BENZYL]AMINO]-6-CHLOROQUINAZOLINE EHNA HYDROCHLORIDE S- (+)-Rolipram 4-(3'-Methoxyphenyl)-2-pyrrolidinone 4-(4'-Methoxyphenyl)-2-pyrrolidinone 1-(4-bromobenzyl)-4-(3-(cyclopentyloxy)-4-methoxyphenyl)pyrrolidin-2-one