| | OXYMORPHONE HCL NARCOTIC ANALGESIC Basic information |
| Product Name: | OXYMORPHONE HCL NARCOTIC ANALGESIC | | Synonyms: | OXYMORPHONE HCL NARCOTIC ANALGESIC;3,14-dihydroxy-4,5-alpha-epoxy-17-methyl-morphinan-6-onhydrochloride;4,5-alpha-epoxy-3,14-dihydroxy-17-methylmorphinan-6-onehydrochloride;morphinan-6-one,4,5-epoxy-3,14-dihydroxy-17-methyl-,hydrochloride,(5-alpha;numorphanhydrochloride;oxymorphinonehydrochloride;(5alpha)-4,5-epoxy-3,14-dihydroxy-17-methylmorphinan-6-one hydrochloride;OxyMorphone HCl | | CAS: | 357-07-3 | | MF: | C17H21ClNO4 | | MW: | 338.80594 | | EINECS: | 206-610-5 | | Product Categories: | | | Mol File: | 357-07-3.mol |  |
| | OXYMORPHONE HCL NARCOTIC ANALGESIC Chemical Properties |
| solubility | DMF: 30 mg/ml; DMSO: 30 mg/ml; PBS (pH 7.2): 10 mg/ml | | form | A crystalline solid | | color | Yellowish-tan powder | | Stability: | Hygroscopic |
| RIDADR | 3249 | | HazardClass | 6.1(b) | | PackingGroup | III | | Toxicity | LD50 orl-mus: 402 mg/kg THERAP15,1208,60 |
| | OXYMORPHONE HCL NARCOTIC ANALGESIC Usage And Synthesis |
| Uses | Analgesic (narcotic). | | Definition | ChEBI: Oxymorphone hydrochloride is a member of phenanthrenes. | | Brand name | Numorphan (Endo); Opana (Endo). | | Clinical Use | Oxymorphone is a potent μ agonist (10 times greater than morphine) that is used to treat severe
pain. It is used by intramuscular, subcutaneous, intravenous, and rectal routes of administration.
The intramuscular dose of oxymorphone (1 mg) has a half-life of 3 to 4 hours. It is a Schedule II
drug. Oxymorphone, because of its 14-hydroxy group, has low antitussive activity. | | Safety Profile | Poison by ingestion, intravenous, intraperitoneal, and subcutaneous routes. An experimental teratogen. When heated to decomposition it emits toxic fumes of NOx and HCl. |
| | OXYMORPHONE HCL NARCOTIC ANALGESIC Preparation Products And Raw materials |
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