- Canadine
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- $0.00 / 20mg
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2023-02-24
- CAS:5096-57-1
- Min. Order: 5mg
- Purity: ≥98%(HPLC)
- Supply Ability: 10 g
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| | canadine Basic information |
| Product Name: | canadine | | Synonyms: | (13As)-5,8,13,13A-tetrahydro-9,10-dimethoxy-6H-benzo[G]-1,3-benzodioxolo[5,6-A]quinolizine;(S)-Canadine;(S)-Tetrahydroberberine;C03329;6H-Benzo[g]-1,3-benzodioxolo[5,6-a]quinolizine, 5,8,13,13a-tetrahydro-9,10-dimethoxy-, (13aS)-;(-)-Canadine | | CAS: | 5096-57-1 | | MF: | C20H21NO4 | | MW: | 339.39 | | EINECS: | 225-815-0 | | Product Categories: | | | Mol File: | 5096-57-1.mol |  |
| | canadine Chemical Properties |
| Melting point | 135° | | alpha | D22 -308°; -317° (c = 0.28; 0.4, both in methanol) | | Boiling point | 475.36°C (rough estimate) | | density | 1.2270 (rough estimate) | | refractive index | 1.6000 (estimate) | | storage temp. | Refrigerator | | solubility | Chloroform, Ethyl Acetate (Slightly), Methanol (Very Slightly, Heated) | | form | Solid | | pka | 6.53±0.20(Predicted) | | color | Pale Yellow to Light Yellow |
| RIDADR | 1544 | | HazardClass | 6.1(b) | | PackingGroup | III |
| | canadine Usage And Synthesis |
| Chemical Properties | Yellow Solid | | Uses | (S)-(-)-Canadine is a protoberberine alkaloid which potently block functional KATP channels natively expressed on midbrain dopamine neurons. Canadine is used for treatment of degenerative diseases or conditions associated with KATP channel signaling. (S)-(-)-Canadine has a strong central nervous system-depressing activity and is used in the preparation of tetrahydroprotoberberine derivatives as new antipsychotic agents. | | Definition | ChEBI: (S)-canadine is the (S)-enantiomer of canadine. It has a role as a plant metabolite. It is functionally related to a (S)-nandinine. It is an enantiomer of a (R)-canadine. | | target | P450 (e.g. CYP17) |
| | canadine Preparation Products And Raw materials |
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